Update on my husband

Hello Irish Terrier

That  continuing undetectable PSA reading is excellent news & being on tablets rather than injections will hopefully be easier to manage going forward.   It's great that he's back doing a little bit of work which is another step of normality. 

Best Wishes

Brian

Hello Sheena (Irish Terrier) 

Thank you for the update - 2 years in and he's doing amazing, still undetectable, it says triplet theapy works. 

Yes a heart attack is something we all think about and hope it never happens to us, so he's been unlucky to have both however. he's getting there with your support and his team. Being back doing a bit of work must also be good for his mental health.

I said in one of my posts last year - I now know why it's called "a journey" - and I share with you all the ups and downs BUT we all share each others problems and together we are stronger. You are both doing great - long may it continue.

Best wishes - Brian.

Thank you Brain it has helped his mental health to do something normal and a chat with the oncologists is always good.

Thank you Brain, We don't think the heart attack was anything to do with the hormone injection but they are changing it for tablets just in case, the statin is being changed because of the interaction with the darolutamide so will have to keep a close eye on symptoms.

The tablets are probably Orgovyx/Relugolix. These are known as a GnRH Antagonist.

Most of the hormone therapy injections (Zoladex, Prostap, Decapeptyl) are GnRH Agonists, with Fimagon/Degaralix being the only GnRH Antagonist injection (which has to be done 4-weekly). The GnRH Antagonists are considered less taxing on the cardiovascular system than the GnRH Agonists. Thay is probably why you've been moved to one. (GnRH is sometimes referred to as LHRH - they're just different names for the same hormone.)

The other tablet form of hormone therapy is Bicalutamide, but you wouldn't be put on these with Darolutamide, as Darolutamide is a more powerful version of Bicalutamide (both anti-androgens).

Thank you Andy62, the oncologists did say the tablets were better for someone with heart problems.