Lower PSA Again !

Hello Dave (Dave HS ) 

As I am not medically trained and your PSA is on it's way down I honestly don't know where you are going with this.

I do know there's something on your MRI and 1 core of your previous biopsy showed cancer but as you said before the cancer/question cancer was in an area the biopsy didn't get to.

It will be interesting what this new biopsy shows - are you having this under a general anesthetic? Oh and my post of 3 months ago still stands - I wouldn't want the prostate "whipping out" without good reason.

I hope it goes well for you next Monday and you get some answers.

Best wishes - Brian.

As ever Brian, thanks for your words of wisdom ! I’m slightly at a positive loss too as to why my PSA has dropped considering when my Consultant was very worried about my MRI and how my initial Biopsy results didn’t correlate to what the MRI was suggesting was potentially happening. Your right and it’s a lesson for us all to not initially panic and give yourself time and try and get the full picture because on my first meeting with my Consultant (who is excellent by the way) he said if this is causing you great upset and worry we can go ahead and operate and take it out. Glad I stuck my guns and waited another few months before going in for another biospy next Monday where they are just going to target the tumour. The chaps who conducted the initial biopsy didn’t comment on the awkward nature of accessing the tumour as to where it was located ! My wife was saying that maybe because my PSA level dropped past 3 months is because I have been under no real stress (I work in a very toxic environment and took a few weeks off work to rest after the diagnosis and have taken a massive step back in terms of what I do in the job. It’s a Longshot but perhaps taking the foot off the gas has helped in slowing things down as in terms of the tumour growth ! As I said It’s a llongshot guess and long May it continue !! 

Hello Dave (Dave HS) 

I agree, I am a firm believer that a positive attitude and the correct mindset is half the battle. By reducing your workload - and the stress may well be beneficial to your results.

I also agree that the investigation into possible cancer needs to be concluded with a result - yes or no.

The only other alternative answer I have is that you have a possible "low or non-secreting PSA". This does happen although is quire rare.

i am sure once you get Monday's results you will have some answers.

Best wishes - Brian.

^Millibob: "The only other alternative answer I have is that you have a possible "low or non-secreting PSA". This does happen although is quire rare..."

Beat me to it. I think most commonly associated with recurrence. My psa numbers do not "match" what one would expect from the advanced spread revealed by PSMA PET, 2.9-4.5 rather than standard >20.

When in doubt do not rely on psa numbers.

Dave.

Good to know Carl as was not aware of that until  Brian and yourself flagged this. Cheers.

Hi Dave, tricky one must say 

After your MRI in the summer and the biopsy then did they give u a Gleeson and  if so did they give you any tumour size in mm from the MRI

Steve 

Hi Steve, Consultant gave me a Gleason 6 score and the tumour size was 2.6cm from what I remember ! 

Ok Dave, are u sure 2.6cm and not 2.6 mm

If it is 2.6 cm then one wonders why they are doing another biopsy and not just starting on a treatment plan....unless I'm missing something.

Actually even if 2.6 mm wonder why another biopsy as u already have a Gleeson, 6 obviously the lowest.

Best wishes 

Steve 

Thanks Steve, yes Definitely 2.6cm , not starting any treatment as only one core sample came back as cancerous (that one was from the Tumour, they took 4 samples from the tumour) Consultant convinced based on the MRI that my Gleason Score of 6 is probably not a true reflection of the cancer contained in the tumour and feels original biospy may have missed more of the cancer so thus why we are going again next Monday with a targeted biopsy and just taking samples from the tumour !! So we go again !!

Ok Dave, it's just with a tumour size of 2.6 cm makes you wonder if getting near the capsule edge.

Probably another MRI would mean more , to see if tumour size increased cos last MRI was 6 months ago.

The other puzzling bit is low PSA with the 2.6 mm tumour although we know about low secretion tumours.

Anyway that's just my thinking and obviously I'm no expert.

Best wishes anyway 

Steve