Raised PSA after operation

Hello Towersaf0ffd 

I am so sorry to read of your increased PSA results. I am assuming that after the surgery you had a meeting with your team and they would have told you the histology from the prostate they removed - did they remove it with clear margins?

As your PSA is rising it looks like they didn't get everything so the next steps will no doubt be a scan to see if they can find where the cancer is followed by a course of Hormone Therapy and Radiotherapy. This of course is my educated guess as I am not medically trained.

Please do let us know how it goes.

Best wishes - Brian.

The post op meeting went very well with nothing of concern for the consultant. He said they didn't find anything unexpected but didn't do any nerve saving surgery. 

Another tumour they didn't know about was found in the post op biopsy 

Hello .  I had a prostatectomy in October 2024.  My first 3 PSA readings were undetectable and then suddenly my fourth reading, which was this month, was .67.   My oncologist called me and scheduled a PSMA scan at the end of the month.  He said the high PSA reading indicates a recurrence.   Good luck to you!!

Hi Towersaf0ffd & Bruceinpaf25275 the main reason for going with surgery quoted on here seems to be that you retain the second line of defence in RT & HT and this is probably where you are heading.  Once you have more info, please ask any questions and we can help you through.  The thing to focus on is that you are both in the ‘curable’ camp.

Getting booked in for a scan and now referred to an oncologist 

Sounds like we are on similar journeys.  God bless us both.  We will both be just fine.   

Can anyone explain why my post prostatic psa( no additional treatment) went from .13 to .04 to .06 to .67 ( all 3 months apart) and then 28 days after the .67 reading it was back down to .06?   Thank you !!

The very short answer is"No".

What did your team say?

Hello Bruce (Bruceinpaf25275) 

I can think of a few reasons but I am probably clutching at straws:

* You had sexual activity in the 48 hours before the 0,67 test. (pump?)

* You rode a bike or had vigorous exercise (in the gym?) in the 48 hours before the test.

* The test with the odd result (0.67) was undertaken in a different testing laboratory.

Only my random thoughts - but they can all increase your PSA readings.

Let's hope it keeps at 0.06 or lower.

Best wishes - Brian.

Hi Bruceinpaf25275 , PSA can bounce which is normally associated with RT or HT but does occur after RP sometimes.  One of the difficulties we all have is trying to interpret single PSA tests.  The key is to look at trends over for example 6 months with 3 readings.  A single blip is either a bounce or an error at the lab!  Your 0.06 is excellent.