Post prostatectomy treatment.

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Good morning. Can anyone give some  insight into what psa level would trigger recommendation for Salvage radiation treatment. Some sources say nothing is done till 0.2 others mention much lower thresholds. Confused. Thank you all 

  • Good Morning  

    This is an interesting question. Don't forget I am not medically trained and I still own my prostate however from what I know and have read, the most common wait is until the PSA is risen to 0.2. I agree I have read of others starting RT at a lower PSA so it looks like it's down to the individual oncology team.

    Let's see what others come back with as I don't have a set figure in my resources.

    Best wishes - Brian.

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  • Thanks Brian. I will await other replies. Again research indicates that there is nothing too see tumour wise at levels below 0.2. Hopefully some further insights will emerge. Enjoy your day. 

  • Hi Sight for sore eyes. I am 2 years post op and my PSA has been rising steadily to 0.4. I am now expecting to have a PSMA pet scan early next year followed by RT without HT. From what I have understand from extensive research on good old Google (particularly USA sites) and discussions with my care team, there is no one clear cut answer to your question. It depends upon the individual consultants view and perhaps the hospital and health authority view and available budgets. The stats from the various studies I have read are contradictary and are not conclusive when compared to each other. My understanding as a layperson is that there are risks with delaying salvage RT that the cancer could spread but then there are also more risks of colateral damage if RT is carried out too soon before the cancer can be homed in accurately from the pet scan. The wait is a worrying part of our journey.

  • Hi Static, Thank you for your reply. Best wishes for your upcoming tests and treatment. My first PSA post RP was <0.03. Last week was 0.03

     I am.not sure if it's significant as its still undetectable in some research. I still await clarification. Not sure if I am worrying unnecessarily or if this is the start of an upward trend. Perhaps closer monitoring may be required. Thank you again

    .S 

  • Hi Static. I don't know whether you have picked up on this video but it might answer some of your questions.

    https://youtu.be/JXRhzi0Z6qQ?si=VBv-v_HIzIOfAZ7H

  • Thank you Alwayshope. I hadn't seen that video. I think it highlights that technique and treatment have come a long way but there is still no best available solution. I suppose that really applies to all medical matters. I had rad about the Axumin Pet Scans in the past but dismissed the thought of them due to their inability to function at relatively low PSA levels. What I found interesting and a bit disconcerning though is that it was said 10% of PC does not make PSMA and it was indicated that PSMA Pet Scans are therefore of no use in those situations. I realised PSMA Scans were not 100% accurate, although they were considered to be the most accurate