Ivermectin for PC

Hi Murcao . This article goes into some detail on the challenges associated with repurposing drugs for use with cancer.

https://www.nature.com/articles/s41392-024-01808-1#Tab3

One success I can think of is the use of the BCG jab (originally developed as a vaccine for TB) which can now be used for people with bladder cancer.

Again, for information, I have attached an article on what the nex years hold for men with prostate cancer at just 1 research centre.

https://www.icr.ac.uk/news-features/latest-features/the-future-of-prostate-cancer-research-what-could-the-next-decade-bring

My fear is that good things come too late for me ,I'm 54 and I live now in panic about how much time I still have to live ,I went to eindhoven to radiotherapy and they refuse radiate the whole pelvic region, I'm scarred now that they don't do it it the netherlands, they only want to radiate the prostate and max 5 lymph nodes, but now they say saw the scan and found at leat 6 ,scared that is true or is an sad escape because I press him that I would want all the pelvis radiated, they advise to ask a second opinion I'm Antoni van leeuwenhoek hospital in Amsterdam, but I'm scared that they also refuse and that reduces my chances of success, Amsterdam it's almost 2 hours away bur I don't mind going there for some weeks for treatment as long as they do it .

We all have wobbles along the way so take things one step at a time. I supplied you with a link to the radio oncologists at that hospital so have a look at their profiles and find the ones who have experience with prostate cancer but also the ones who have links to trials. From what I understand you have a choice of where and with whom you can have a second opinion and then make your application. Once you know who and when the appointment is with make a list of your questions and maybe send them to the doctor before hand so that they know why you have asked for a second opinion. Until you have the second opinion you won't know what you are facing. No matter what, there will be a treatment plan. Your research has led you to believe that whole pelvic radiation will give you the best chance of long term survival but if the doctors disagree then it is incumbent on them to explain why their recommendations are better for you. 

Can I suggest you look at this link and take a copy of it to the meeting.

https://prostatecanceruk.org/about-us/projects/best-practice-pathway/

In section 2 there is a treatment pathway flowchart link which shows the options under either EBRT, BRACHYTHERAPY. These are the NICE guidelines (UK) but in line with the European Guidelines. 

Get your evidence together which includes copies of your scan reports as at the moment you only have their word for what it says.

 Murcao What are your statistics PSA/ gleason,  I know you’ve posted before but I can’t remember. Why do you think you need full pelvic RT? It’s not something that is common or needed because most PC is contained and easy to target. And when it’s spread and found in distant places Chemo is the usual approach. The treatments are so good now. Please don’t seek answers in random un proven places as you are wasting your time and potentially can cause damage to yourself, the last thing you need is to strip the good bacteria out of your gut.  Radio therapy / chemo and hormone treatments are used for a very good reason - because they work. Discuss with your consultant why they think the treatment is the best for you. We’ve all  panicked .

What did your consultants say about your PC ? 
L

I have a T2cN1M0 ,at 2 weeks ago they said I have 5 positive lymph nodes last week the radiologist said it was for sure 6 and that's annoying because they say they only radiate 5 at the most ,when they radiate the lymph nodes they say it's curable but one or two extra isn't curable anymore and that's sad to hear. 

Forgot to say ,all lymph nodes are in the pelvis, oncologist said because low volume and outside the pelvis she saw no reason for chemotherapy. 

Well I can see how frustrating that is ! If you are doing 5 do the 6th while you are there! T2 c is quite low. You don’t need to panic yet and you certainly have lots of time to say you are not happy and seek a second opinion. It’s hard to know what to say as you are in a different country and I have no idea how your system works. Definitely do some research on what’s available. I know it’s random but you could email or phone the Royal Marsden in London and ask them for advice of where to go in your country.
L

Thanks a lot ,you're right ,it's very frustrating, when you listen that because of one or 2 lymph nodes they refuse you the best chance of surviving it's very scary, I panicked yesterday when by telephone the radiologist told me they only go to 5 and they saw 6 mayyyybe 7 and because of that you are left aside ,sorry being so annoying but I'm  really stressed. 

You are not annoying at all. We’ve all been in your shoes and it’s a very frightening time. The hardest thing is not knowing what to do or where to go for help. There is no need to panic - prostate cancer is a slow growing cancer in most cases and very treatable. It’s a very very small % people that are terminally ill with it and yet the medications and treatments are so good they are able to live a long time with it . With T2 you have a lot of time to investigate what is right for you and have time to talk to professional people in this field to see what’s best. 
L

Don't forget that however I'm T2c it's already spread to the pelvis lymph nodes ,when I made the scan and saw the diagnosis, it was there clear ,the tumor as not broken the prostate capsule, I was excited then they wrote with spread to pelvis lymph nodes ,and then my world collapsed and I felt smaller than an ant ,but you all know the feeling, that's why it's so much easier to talk with my prostate family, you guys, people who haven't been diagnosed have no idea about what feelings we are talking about, I talk to my brother and he replies that he understands what I'm feeling, but we all know they have no idea ,and I hope they never will.