PSA increasing but MRI shows PIRADS 1 \ enlarged prostate

Hello Gramski and no you are not an imposter. Yes the forum is mainly involved with prostate cancer but it has to start from somewhere. Your initial PSA was of concern to the doctor so they have given you an MRI to give you a baseline. With the Pirads I this is very unlikely to be clinically significant prostate cancer and would normally be monitored with regular PSA tests but your PSA is increasing at a higher rate than expected. I presume that any form of infection has been ruled out and that you did not cycle, have sex or vigorous exercise within 48 hours of the PSA test?  As there are no clinically significant lesions then there is no 'target' for a biopsy so check what kind and how many cores the experts propose to take if you have one done. I cannot answer your question but hope that someone with personal experience will come along and help you out.

In early 2022 I had an MRI scan because of a raised PSA.

My prostate volume was the frankly ridiculous size of 112cc.

A lesion of PIRADS 2 was found, and deemed "not clinically significant".

2 years later I the same figures were PIRADS 5 and 120cc! ().

When the biopsy was done I was diagnosed with Prostate cancer Gleason 9, thankfully still in the "curative" stage. Hormone therapy has started and radiotherapy will follow.

Since we are all individual human beings and everyone's pathway is different, it is unlikely that you will follow the same pattern, but it is possible.

Perhaps questions about when a follow up MRI could be done to follow up on any increase in lesion size so that if it becomes larger you can get right in with a biopsy.

Of course, given the results you have, it is very likely that BPH forms the whole story. 

If it continues to grow it can cause havoc with your lower urinary tract, the symptoms of which are the same as PC.

These sneak up on you without you realising over a period of time, changing slowly enough that you you don't really notice. 

I didn't until the hormone therapy started to shrink the appropriate bits, and then everything began to work at more or less full force again. 

Perhaps you need to compile a plan, a list of what to watch for and then, as we all do. Get on with life. 

Smile at people. It really confuses them. 

Steve

Thanks - the biopsy discussion went the way you mentioned and the consultant also stated that if there was cancer, and if it was detected by the biopsy then it would mean AS awaiting further PSA tests and a future MRI before having treatment at a suitable time. 

Given that many "ifs", the biopsy seemed didn't seem a good idea at this moment in time. I don't want to get complacent but I have read so many amazing and inspirational posts that given my results I don't need to worry unnecessarily.

I'll see what the next PSA test in November has to say; I'm aware of all the things to avoid prior to it so will prepare accordingly. I'll update this thread then in case anyone coming along in the future is in a similar position.

Thanks again. Take care.

Thanks Steve - I live in London so smiling realy does cause confusion and yes; I'm getting on with my life. I'm not a worrier by nature and reading through the journey many individuals and their families are on then I realise how lucky I am at the moment.

As I mentioned in my reply to Alwayshop, I just want to make sure I don't get complacent. But regular PSA tests and another MRI scan at a suitable time is something that I will discuss at my follow up rather than a biopsy.

Your profile has been enourmously helpful and I wish you well on your continued treatment. Thanks again and take care.

I like the variation to the avatar. Now everyone will be imagining me hopping around as we head off for an ice cream treat today.