PSA tripled in a month

2nd generation hormone therapies are the Abiaterone, Enzalutamide, Apalutamide and Darolutamide. I would encourage you to watch the video I gave you a link to where it discusses current available treatments and explains when they should be used.

So he's having his ORIGINAL biopsy retested? Mine was done in 2014. Surely they won't still retain the biopsy sample, will they?

My husband's was 2020 but he also had a biopsy on lymph mets in 2022 which could have been used. Basically any biopsy material is suitable from anywhere in the body which confirmed prostate cancer can be suitable. I don't know how long different countries keep the biopsy samples for.

My only biopsy was done in 2014 at the QE Hospital in Birmingham when I was still living in the UK 

Oh shoot, I forgot to add that to my profile.Yes, I was started on Zolodex immediately in 2014 and still get 3 monthly injections.

There is a tablet called Relugolix which has recently been approved for some men which may be suitable instead of the Zoladex. Just throwing ideas out there.

In general, a period of 10-20 years is a lower-limit guideline for retention. Major institutions prefer to store their slides and tissue blocks for 10 years, whereas cancer referral centers preserve them for 25 years [1].

May I ask what was your original stage 0-4?  I am so sorry you are going through this!

Hi Tom

I'm sorry but I don't understand the question. Could you please elaborate?

Is that likely to have an effect on my PSA levels?