Perineural invasion?

Hi There

I’m sorry both your husband and yourself have been having such a rubbish time. 
I think the cribform you ask about is to do with how the cells look, there are lots of features that make up a diagnosis such as Gleeson score and tumour stage and whilst cribform I understand is something that can be an adverse finding I think it will depend on the whole picture such as the stage and such that will make up a prognosis and treatment. 
My husband recently went to Christie’s to discuss treatment plan, he has Gleeson 9 which is classed as high risk but has had a Radical Prostectomy this week. 

As you will know you could hardly get any better than The Christie so he is in his hands. 
I’m sure others will come along to offer more info for you. M take care 

Hi Annieo e, 

Thank you for your kind reply

Tumour 2/3  Gleason score 8 grade . I totally agree about Christie, we were there everyday for 7 weeks upto October last for his other cancer, which was T4..they were wonderful. Hubby is now in remiion as of Jan, he still goes for checkups every 3 months, he was there yesterday, the consultant said, he really couldn't believed how my hubby has responded and recovered, his words '" it's just rerkable how you are, your cancer was stage 4, you can't get higher"!....we didn't actually know what stage exactly, didn't want to know.....anyway, we have been told today to expect a call from Chrise's next week...as lovely as they are there, I really didn't want to see them again.....wishing you and your husband all the very best for his upcoming treatment 

Xx

No idea where the random smiley faces have come from!

As I understand it the stage 2 or 3 is curable and although on high side G8 is better than 9 or 10. Have they mentioned a bone scan I think it’s usual in the diagnostic process? What was his PSA. My brother law has same diagnosis head and neck and is 6 years remission treated at the Christie so we know how good they are. 
feel so sorry you are having this again so soon. Not fair x 

Hi, They are arranging the second scan ( bone)  next week I understand, he has already had prostate scan.  His PSA level is 10  but, the consultant said, the number really isn't the important bit, it's the trend, unfortunately, my husbands number has been on the ' upward''trend quite rapidly  .which is why the speed of all this... unfortunately, his brother had the same, as did his father...so, they are going to get on top of it.

Xx

The reason I asked about the PSA was that when I was very worried about my husband as his is Gleeson 9 and I was so worried about bone mets I was told by one of the specialist nurses that bone mets are  unusual will lowish PSA so as his is quite low I would of hoped it was a good sign although I know not guaranteed. 

Hello Worrypants1 

Below is an informative post by our very own Alpine Wanderer which might answer some of your questions.

https://community.macmillan.org.uk/cancer_types/prostate-cancer-forum/f/diagnosis-and-treatment/269821/cribriform?_gl=1*18668wf*_up*MQ..&gclid=EAIaIQobChMIx9DnvMPthgMV5JdQBh2WowmrEAAYASAAEgLrofD_BwE&gclsrc=aw.ds

i hope this helps.

Best wishes - Brian.

Hi,

1. I think going through the awful time last year, I am slowly realising that things are what they are at any given time...I only listen to the oncologist and consultant now....we got a nasty shick last year listening to one of hospital specialist Nurses, they really do try to help, but, they are not the experts. My husband's consultant has already said, part of your plan will include a full body scan, 

• Look into the possibility of surgery ( although not likely) due to the damage in my husbands throat from last year's radiotherapy....it would be extremely difficult to tube him for surgery, so, more than likely radiotherapy, hormone treatment and will discuss any other possible treatments....

Take good care 

Xx

Hi 

I have come to realise how different doctors have totally different styles in how they speak to patients and even from the first consultant making us feel like it was a death sentence to the now second consultant  making us feel this is curable and he has a good chance! I can’t underestimate how you must of gone through the wringer with the other diagnosis and feel you must caution yourself against further shocks. 

I hope all the other tests come back negative and that his treatment plan starts soon x

Hello Worrypants1 &Annieone 

I hope you don't mind me jumping in - but, for the rest of the Community to give you the best advice can I ask you to put a little bit of information in your profiles. A bit about your journey to date and Initial PSA, Gleason Score and TNM staging.

To do this on your home page click on the chair - top right. Then "Profile" then "Edit" - once you have written something just click on "save". You can read a member's profile by clicking on their name or avatar.

Thanks - Best wishes - Brian.