Psa up despite Abiraterone and RT

Hi M and welcome.

I am a bit puzzled, u say that you  have already had Chemo although not in the bones.

Normally RT and HT is given first unless possibly because in many nodes as u have mentioned.

As far as the PSA goes I think too early to say, it is still very low.

I think you need a couple more over time to see if an upward trend.

Worrying I know but could also just be a blip as u say.

All the best

Steve 

Hello Mcjc  A warm welcome to the online Prostate Community

I can understand your worry - any rise in PSA is worrying, although PSA is only an indicator and results can vary from one laboratory to another.

My personal view is you should be retested in 3/6 months to see if the increase is a general rise in the PSA or a one off. I am sure your oncologist will be able to give you some answers.

Keep us posted with your progress.

Best wishes - Brian.

you are talking fractions of a point , dont think you have anything to worry about 

you could have 3 tests in a day and everyone would be different according to my old opodi nurse 

i found if i went for a test after work it was higher than if i'd done nothing before the test 

mine has varied from a low of 0.04 to 0.1 , 5yrs on abiraterone now 

Hi Mcjc.

We have just come back from seeing the urologist for a Prostap implant. Where we live the urologist and oncologist work closely together so any concerns are dealt with immediately on the phone. My husband has no bone mets but does have pelvic nodes plus distant mets. He had radiotherapy initially, followed by chemotherapy and has also been on Enzalutamide but his PSA has started to rise slightly so, like you, we wondered what was happening. We have been reassured that it is much too soon to think the worst. We will need to have more PSA tests to see whether it is a trend upwards, or whether it is a one off - we had a COVID vaccination the previous week and this can affect the lymph nodes, as can any infection. Your PSA has been very low and it is usual to wait until 3 consecutive increases in PSA, or a rise of 2 above your nadir, before further investigation is instigated. The next step would then be an MRI, CT or PSMA PET scan to see if there is any spread.

I hope this gives you a little reassurance.

Hi McJc

Your right it’s just a blip, of course it will climb over time, mine was 0.0045 now its near thirty over seven and a half years later, the PSA is not the most important thing, it’s where the cancer is or spread to, I have recently had a ct scan and as the main guy put it, all my squiggly bits are fine just my backbone which has a tumour in it, which iam waiting for an mri this or next month. So don’t worry or stress.

Stay safe

Joe

Hi Mcjc,

My partners in a similar position. original PSA 115, RT and Abiraterone. His PSA has gone up in the last two monthly blood tests, but by such a minuscule amount (0.04 - 0.06)  that I think it's just worth casually watching at this stage, I'm thinking just a random undulating thing. I'm trying to train myself not to overthink any up and downs in the bloods now, as for the last two months I've been convinced he had secondary liver cancer looming with a high reading only to see it now heading back down towards normal . So I understand your anxiety. I'm personally going to keep an eye on things, but try to only allow myself to worry if it starts getting towards 1. and the speed of it getting there.

L

My husband is T3a N0M0 been treated with RT and HT with intention to cure - so slightly different to yourself. Our oncologist told us that his move from 0.026 to 0.034 was 'miniscule'. He will only be worried of the PSA goes above 2. No chemo and no Abiraterone has been needed to date. HTH