Gleason 6 new diagnosis please advise

FormerMember
FormerMember
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Hello

I would really appreciate peoples advice and experience.

My father was diagnosed with prostate cancer yesterday over the phone! They said he is a Gleason 6, low grade cancer, localised on the left side of prostate, 7mm. He is 70 years old. His PSA levels around 5. 

They are recommending active surveillance because it’s likely to be slow growing. 

He has many symptoms, frequent urinating, unable to hold, burning, unable to fully empty etc. 
I did ask the doctor why they wouldn’t recommend treatment right now since he has many symptoms. Dr saying the symptoms could be bladder related and separate from prostate cancer? I did not fully understand why he’d think that. It was these symptoms which led them to scan and find cancer. 

My dad was also on finesteride. Doc suggested he stops that because his prostate is in fact quite small (26…) and it’ll do more harm than good. 

Surely since the cancer has been detected, we should try and cure it right now before it spreads? We are scared that if we wait, it’ll spread (despite it being slow growing), and then he’ll be older, making treatment more difficult. 

Has anyone had treatment for low grade cancer? Would you advise we wait or just get on with treatment? 
Any one on active surveillance then moved onto treatment?

So confused. Please help. 

  • FormerMember
    FormerMember

    Hi Mike, a Gleason 3 + 3 is a low grade cancer grading ( the lowest on the scale ) and indicates a tumour that is likely to grow very slowly if at all, and not a high risk to spread. The reason for recommending AS is that whilst curative prognosis would be excellent, the side effects of any treatment are significant and would impact quality of life.

    I too was recently diagnosed with a 3+3 but unfortunately my PSA was a bit higher which increased my risk, hence AS not offered as an option. 

  • Hi Mike 

    With a Gleeson 6 , low PSa and small size tumour your dad is a good contender for AS.

    The idea is to monitor the situation and if the tumour grows significantly or gets near to the prostate border then treatment could start 

    I was on AS for 4 years and it went ok 

    With a smallish prostate not sure why he is on Finesteride. His bladder issues could be down to an infection, that needs further tests.

    Regards

    Steve

  • FormerMember
    FormerMember in reply to Grundo

    Hello Steve

    Thank you for replying.

    He’s had symptoms for many many years, but they put it down to enlarged prostate. It was all an assumption that it was enlarged, so they put him on finesteride. Don’t think it can be an infection for that many years. Im still not sure why the Dr would think symptoms separate from prostate cancer.

    With tumour being small in a small sized prostate, wouldn’t that be relatively large? 

    if you don’t mind me asking, after 4 years did it change from gleason 6? I’m just so worried that that mri is in years time. What if it progresses before then. 

  • FormerMember
    FormerMember in reply to FormerMember

    Thank you for replying. 

    If you don’t mind me asking, did you have symptoms? 

    I am not sure why the Dr saying symptoms separate from PC and we should be investigating the bladder and use bladders meds. Despite all symptoms being indicative of PC and now being diagnosed with PC. 

  • FormerMember
    FormerMember in reply to FormerMember

    I had  frequency and urgency symptoms for many years and was diagnosed at the time with prostatitis. I wouldn’t have thought to raise again either my GP but he was astute enough to order a full set of blood tests  ( which revealed the raised PSA ) when I consulted regarding another condition. I am so glad he did, it means I can be treated when the grade is a low one .

  • Mike 

    As they r suggesting to come off Finesteride could be worth a go to see what happens.

    For a couple of reasons I only had the one biopsy, Gleeson 6,  the thing that spurred me into action was tumour size increasing From 3mm to 12mm over 4 years plus it was near the border.

    With your Dad's stats being so low yearly MRI should be fine but I also had quarterly PSA which was a good monitor as well.

    Steve

  • FormerMember
    FormerMember in reply to Grundo

    Thank you for replying. 

    we have not been told whether it’s near the border or not. 

    They suggested quarterly psa and mri after one year. 

    I’m extra concerned about AS because he’s already 70. Waiting to see what happens would be he gets older and potentially other health issues making him unsuitable for treatment.  

    It is reassuring to know you were on AS for 4 years. We are worried being on it for even 1 year.

    Based on what I’ve told you, and you’re experienced fo AS and then treatment, would you also think AS is best option for him at the moment?

  • FormerMember
    FormerMember in reply to FormerMember

    Thank you for replying.

    I am guessing your probably a lot younger than my dad too, that’s why they also recommended treatment. 
    With my dad being 70+ they’re probably thinking he doesn’t have a long enough life expectancy to do anything maybe.

  • I  would give AS a go at least. Don't forget there are possible side effects from treatments, also your dad does have existing urinary issues which could exacerbate existing problems

    Possibly also consider going with what the experts r recommending.

    Steve

  • FormerMember
    FormerMember in reply to Grundo

    Thank you Steve. Honestly has helped chatting to you. 

    We were panicking about AS thinking the MRI will be one year away and a lot can change in a year. But seeing as people have been on AS for 4 years, it is reassuring.

    All the best for you and thank you again