Hello, I’m in remission after the big op and 6 lots of chemo. Now been on PARP inhibitors (Niraporib) for 3 weeks. I’m now getting daily waves of sickness which I did not have initially and also so fatigued by 6pm (even after a post-lunch nap) that I go to bed. I wondered if others had this experience, whether it gets better or worse, and if it’s worth sticking it out? Anyone have any advice for me? Pooky x
Hi I too had the surgery and chemo and on the same parp drug . I had to take anti sickness and the fatigue was almost unbearable even walking was an effort , so I told the consultant and he decided to reduce the dosage from 600 mg to 500 mg and made a massive difference . Haven’t needed anti sickness and the fatigue has gone so don’t give up talk to your consultant and that might work for you .
Hi I too had the surgery and chemo and on the same parp drug . I had to take anti sickness and the fatigue was almost unbearable even walking was an effort , so I told the consultant and he decided to reduce the dosage from 600 mg to 500 mg and made a massive difference . Haven’t needed anti sickness and the fatigue has gone so don’t give up talk to your consultant and that might work for you .
That is really interesting and quite reassuring to hear. I will talk to the consultant. I was going to ask him if it was really worth continuing the Niraporib and if it really makes that much long term difference. Trying a reduced dose makes much more sense. Thank you for replying.
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