Kidneys during first chemo

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Hi all, 

my mum started her chemo today (carboplatin & paclitaxel) after a full debulking 8 weeks ago, she’s stage 3c high grade serous.

About an hour into treatment her kidneys decided they didn’t like it, she said she felt like they were going to explode. She was taken off chemo, had an antihistamine and a 30 minute break and then back on. She was able to last the rest of the treatment and is now back home.

the nurses told her this is quite normal for the first round as your body reacts to it, but I just wanted to ask if anyone else had experienced this and if it caused any issues for subsequent treatment? She is due to have 6 rounds in total and then 2 years on PARPs.

Thanks in advance for any help. X