lenvatinib side effects

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Hi, I'm 2 weeks into taking lenvatinib alongside 3 weekly pembrolizumab infusions, I was wondering whether anyone else has been on these drugs and how long side effects lasted? I've had high blood pressure, headaches, fatigue and muscle and joint pain.

  • Hi  

    I’m Anne, one of the Community Champions here on the Online Community and, although I'm not a member of this group, I noticed that your post hadn't had any replies yet. Responding to you will 'bump' it back to the top of the discussion list again.

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  • Sorry, missed this one.... I've been on just Lenvatinib for a year now, with different side effects at different times... but it's working - metastatic thyroid cancer (skeletal) stopped growing and some shrinkage, primary kidney cancer (that was awaiting surgery) shrinking like crazy!

    Side effects are unpredictable, but mine seemed to appear after a  2-3 month period. They also disappear after a 3-day Lenvatinib holiday, and come back as something different 2-3 months later! I've had stinging mouth, dizziness, stomach cramps, taste changes, hurty feet, nausea, vomitting, no appetite, weight loss....

    Oncologist has another patient been on it for 7 years..... says most people stop when a side effect becomes unbearable. Not me,at least so far!

    Regards, Keith