Help with SPEP & IgA result

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Hi there,

My GP has run an SPEP recently on me and the result was total globulin 34 g/l and IgA 367 mg/dl. My ESR is also high at 22. Creatinine is 90umol which again I've read is on the higher end of normal.

I have read these fall within normal range, but are in the higher end of normal.

GP has now requested urine sample for BJ protein.

I have had ongoing pain in my hip for around 2 years now, shoulder pain for approx. 6 months. Physio hasn't helped at all so they suggested I request an x-ray of my hip and shoulder. GP is arranging x-ray on hip and ultrasound on shoulder.

 I have MM in my family but I also have idiopathic intracranial hypertension which I've read has a link to MM.

I understand until the urine is tested there's no definitive answer but I was wondering if anybody has had "normal" SPEP but still been diagnosed with MM? 

Thanks, Kate.

  • Hi Kate/ and a very warm welcome to the online community which I hope you'll find is both an informative and supportive place to be.

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  • Hi, 

    I hope you are well.

    Your post caught my attention because I am in the same boat.

    I am 40 and I have abnormal blood tests.

    CBC: Low mch, Low mchc, Low neutrophil, Low vitamin D, Low folate, 10% Hypochromasia but normal ferritin. 

    Liver Function: slightly high serum protein at 81g/L but normal Albumin. 

    Globulin IgA slightly high at 289mg

    Serum Calcium: slightly high at 2.60mmol

    GFR: 85 dropped from 90 in one year.

    Serum Creatinine: 86

    Symptoms I have: feeling general body aching and weakness.

    please let us know when you have an update.

    thank you