Hi - my first time posting.
I was diagnosed with pleural mesothelioma in November 2023. I was lucky and didn’t need treatment just CT scans every 3-4 months. In September 2025 I was started on immunotherapy. This helped reduce my small tumours but unfortunately I got really bad side effects very quickly, the worst of these being immunotherapy induced colitis in November 2025. I was prescribed Prednisolone steroids. The side effects of this was even worse! I still have the colitis but it’s so much better and I’m no longer on Prednisolone. Unfortunately I can’t get rid of or relief from side effects. I’m not even sure what’s actually causing them. The worst is itchiness (no real rash). My lower legs and feet in particular get very red, swollen and sore.
I’m looking for advice to help with these side effects. I’ve used various creams including Zerobase but only get very limited relief. I’ve also been prescribed strong antihistamines. Does anybody have any suggestions please?
I’ve been told I cannot go back on immunotherapy because of the side effects. Makes sense as it was causing more problems than the disease! Even though I haven’t had immunotherapy since Christmas my mesothelioma is still stable but that won’t last forever. My only option then will be chemotherapy which kind of scares me.
in the meantime it would be great if someone had any advice to help my side effects. Thank you
