Started 2nd cycle of targated therapy

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Hi Just started 2nd cycle of targated therapy and red lumps have appeared on my lower legs. Very must like mosquito bite.

Also legs feel very heavy and ache any body else had this experience.

Consultant wants me to stop meds for weekend and try steroid cream and review again Monday. 
Would love to hear any body else experience.

regards Bees 

  • Hi  

    I don't know what sort of targeted therapy you are on but when I was on Dabrafenib and Trametinib I would occasionally get sore, red lumps on my arms and legs. This corresponded with my neutrophils (white blood cell count) being low. A break for a few days usually sorted it out. 

    If you develop a fever etc contact your helpline number in case it's an infection and you need antibiotics. This happened to me a few times as low neutrophils affect your ability to fight infection. 

    Of course, this could all be irrelevant to you! 

    I hope you are feeling well and the weekend break resolves the issue. 

    Wishing you all the best. 

  • Hi Dunes,

    Yes I’m on those same drugs and it sounds exactly like the lumps on my legs. My body aches aswell so yes all could be related. 
    Doesn't help kids have  gone back to school and they all have colds!

    Thank you so much for your reply as it really helps to get advice as it calms the constent worry in my head! Rolling eyes

    Thanks again.

  • No worries, I'm happy to answer any questions based on my experience. 

    I hope you are starting to feel better now. Yes, I frequently felt achy and flu like. When it built up I would need to have a few days off the drugs. I learned this after ending up with neutropenic sepsis and stays in hospital a few times. My dose was also slightly reduced due to the neutrophil issue. So do listen to your body and don't struggle on if you feel really poorly. 

    I made it to the end of the year and I'm glad I did it..

    Take care and best wishes x