Help - Need advice on Letrazole & Exemestane please. Abemaciclib & Fulvestrant no longer working.

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My current Endocrine treatment ( Abemaciclib & Fulvestrant) isn’t working anymore & my cancer has spread. I need to decide on a new Endocrine treatment, between Letrazole or Exemestane. 
Does anyone have any experience of either or any advise please. 

  • Hi , I don't have experience of any of these but as your post has not been answered me replying to you will get your post bumped back up to the top of the list where hopefully someone you does might see it this time and reply to you.

    Wishing you all the best with your treatment x

  • Hi Lucifer I have been on Exemestane and it was a breeze compared to Fulvestrant and abemaciclib which I'm now on. 

    I took one tablet a day and had no side effects at all, but everyone is different.

    Good luck x

  • I’m on letrazole , seems fine 8 months excellent response both scans , no side effects so far and minimal wt gain , fee mood swings x

    • Hi! I've been on letrozole for 2 years, it has stopped working for me, but I was fine with it overall. Hope you're the same  Kissing heart could o please ask you? As letrozole is no longer working for me (tumour double on size) I have been offered the 2 things that aren't working for you bit I am reluctant to do so. How were you with them? If I choose not to try them, I have been offered examestene, same as you xx
  • Hi, just come across your commi, I've just been offered the fulv/abem combination bit I'm really reluctant because of the side effects. Are you saying you suffered badly? My other option is the examMuscletene, which is what I'm leaning towards. Thanks in advance & hope things are going well for you Muscle

  • Hi Liesel, We decided to go for a different option of Exemestane & radiotherapy. Been really bad with side effects of radiotherapy but so far Exemestane has been ok as long as I take it with food. I get really bad indigestion otherwise, but that could also be the radiotherapy side effects. 
    Thank you for replying & good luck with your treatment too. 

  • Hi LabradorLass, 

    I was on Fulvestrant & Abemaciclib for about a year but they stopped working. Now on Exemestane. I didn’t have any side effects from them, just a bit of a sore bottom from the injections not bad just a bit annoying. Hope all goes well & take care. 

  • Than you for the info. Glad to hear you had no bad side effects. It's really chewing me up but I've got another couple of weeks to decide. Good to have feedback from someone who's experienced it. ThMuscleks again & good luck to you MuscleKissing heart

  • FormerMember
    FormerMember

    Hi I was on exemestane after my treatment finished and found it caused a lot of pain for myself... I'm now on letrazole and have been for 3 years now and have no side affects 

  • Hi, thank you. My side effects of letrozole have been minimal , it's just stopped working unfortunately Disappointed relieved what type of pain were you experiencing with exemastane if yo don't mind me asking? Thanks so much for your reply and lots of luck and health Muscle

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