Ambiciclib

Hi Pooh bear gosh that seems like a lot to be dealing with, I'm not surprised you're struggling. It might be worth talking to your medial team about the risks of stopping the drug, so you can make a more informed decision.   You might also want to chat things through with the lovely folks here at Macmillan, the number is 0800 808 0000. They can not only provide a listening ear, but can recommend other support and expert advice.  I hope things get easier soon, best wishes 

Hi Pooh Bear, I am 14 months into Abemaciclib and am also struggling and I’ve not had nearly as many difficulties as you have. I’m really sorry to hear about everything you have been going through. Have you spoken to your oncologist about having a break ? I have had a few weeks off after an infection and  had so much more energy. I’m going to ask if I can have a few weeks off for my wellbeing. The breast care nurse mentioned that letrozole could be contributing to the struggles - so that’s something to consider, and discuss with your team . Also a reduce in dosage? . I’m on 100g after a reduction from 150 at the start, maybe a reduction to 50 is better than stopping altogether. My lack of productivity gets me down but the tiredness is very debilitating. Perhaps we have to embrace the rest on this medication…but I know that’s not always possible. Whatever you decide about stopping or continuing, we’ve done well to get this far on Abemaciclib 

Thank you, I forgot about asking for it to be reduced. I am also on 100mg. I am having some extra blood tests, and if these don't show anything, then I will talk to my consultant on my next visit. I don't feel if I am getting much support from them anymore, they are just blaming everything else for my problems, and saying it's not the tablets. I have had breaks every time I have had an infection, I think this maybe the longest time I have been on them without a break, 3 months, they were last stopped in February for 3 weeks.