Hello I have received six cycles of kadcyla and now have peripheral neuropathy in my feet. Oncologist paused treatment and said my seventh cycle would be half the dose to allow my feet to recover. I have been taking Gabapentin for five weeks and feet are still tingly. Due a telephone call with oncologist two days before 7th cycle and I think after I tell him my feet still tingly he may discontinued kadcyla and switch to herceptin.
I am/was HER2 positive, Grade 2 Stage 3, had chemotherapy x 6, lumpectomy and second surgery as did not achieve clear margins first time, radiotherapy x5, 6 out of 14 kadcyla.
Has anyone had to switch from kadcyla to herceptin? I am concerned as read kadcyla has 88% of NON recurrence compared to herceptin 77%.
Thank you
Hi Sandra D sorry to hear you're having issues with neuropathy, how frustrating. Like you, I was HER+ and I had chemo, lumpectomy and radiotherapy. I wasn't offered kadcyla, just 18 cycles of Herceptin. I know we all have different variations and therefore different treatments but I just thought I'd share.
As you almost half way through the kadcyla, I guess asking the oncologist about the effectiveness of the treatment to date is something to consider as well as the implications of the switch. Best wishes
Hi, yes, clear margins and to be fair, the chemo killed everything beforehand so I had no active cancer cells left. Herceptin was fine. I had it as IV along with chemo for the first 6 cycles then I switched to 12 phesgo injections. No side effects whatsoever with these. Best of luck in getting a clear plan that works for you going forward.
