Commencing Letrozole..? When

Hi I too have been prescribed  Letrozole, but only start radiotherapy in a week or two. I read somewhere to take the drug after radiotherapy, to deal with side affects of both if any one at a time. Is this so or should I take Letrozole before radiotherapy? An6 thoughts? 

Hi I was diagnosed January, lhad umpectomy February 7th and radiotherapy mid April. The breast surgeon prescribed Letrozole at end of February after I had a blood test to check if I was post menopausal. When I discussed taking it with the surgeon I said I was worried about taking it and needed some time to consider side effects versus the benefit. He said that was fine. When I  had my consultation with the oncologist I had decided I would take it and spoke to him about it and he agreed for me to wait until 2-4 weeks after radiotherapy was over so I  didn't have 2 lots of side effects. I've been taking it for 1 week now so probably early to say what side effects are. I have felt fatigue some days but that could be the radiotherapy side effects as well. My cancer was downgraded to stage 1 and found to be smaller and less aggressive than expected when they removed it  so that was also a consideration that I could afford to take some time to think about it. Sending hugs and best wishes xx

Hello,  I started Anastrazole after radiotherapy.  However if there is a long wait for radiation the aromatase inhibitor may be started earlier.  Take care of yourself.  I have been on anastrazole for 2 years so every year a celebration.  3 more years to go!!

I started 4 weeks after surgery . Radiotherapy markers tomorrow ( 8 weeks after surgery ). You can calculate your benefit in PREDICT , if you have  all the info 

https://breast.predict.nhs.uk/

it’s what the oncologist will use . 

Thank you so much for taking the time to reply. I too was diagnosed in January, but mine has been a longer time scale. I had lumpectomy March 14th, and re-excision 29th April (results took a while to come back). I have now been referred to oncology, but that will take a couple of weeks or so to be seen. I have to wait around eight weeks from the second surgery to start radiotherapy. I am 71  with  lobular cancer, 2.5 cms, grade 2, er/pr positive, Her2 negative, node negative and no lympho-vascular invasion. I too am concerned re: side-effects of letrozole. I declined onco-typing. I would prefer to see the oncologist before commencing letrozole, but I'm starting t worry about time-scales. Sending love and hugs to you too xx 

Thank you so much for your reply. Sending love and best wishes xx

Thank you so much for replying. Do you mind me asking if you were you offered oncotyping?

Mine is lobular , same grade and 2cm , node negative . The onco wasn’t pushing the Anastrazole but I said I would start it before radiotherapy . I’m sure you’ll be getting a pre radio appointment so

Would you mind me asking if you were offered oncotyping?

Not originally ,,which is what held up my radiotherapy (but also had a reaction to post op dressing , so couldn’t have had it anyway).

predict had me as low risk , so I didn’t meet NHS criteria . BUPA funded it , came back as 18 ( post meno ), so no chemo . But at least I know now .