side effects of Letrozole tablets

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Hi all,

I have been on Letrozole tablets 2.5mg for about one year now following chemotherapy and radiotherapy sessions.

Does anyone have any experience of the side effects (my legs ache and my fingers feel stiff first thing in the morning). 

Thank you all and compliments of the season to you all!

  • Hi Flagon

    Yes I get both of those side effects on Letrozole- my fingers are also sometimes very painful in the morning as well as feeling stiff but they do get better as the day progresses.

    Best wishes

    Lizzie

  • Hi

    i had my surgery in July2022 lumpectomy and node clearance then radiotherapy and have bisphosponate infusions six monthly . I have been on Letrozole for 16 months and the side effects are really difficult . I am 71 years old and had mild arthritis before my cancer diagnosis but the pain now is very bad . Mainly in my hans, wrists , ankle and front of feet . I have started to wear a splint at night as my fingers keep locking ( obviously carpel tunnel which I believe can be a side effect of the tablets ) . The pain has been worse now the weather has gone colder and damper . I do all the stretching exercies at least twice daily and walk and to avoid lymphoedema in my arm where the nodes were removed I massage gently with a baby brush twice daily . All advised by the breast care nurses. My eyes are dry, I itch and have dryness down below all relieved by cream and drops from the doctor. 
    My doctor has stated on my prescription that I am to have the Accord brand only Letrozole which seems to agree with me the most. My hot flushes are now almost non existent. 
    the pain is my main concern and nothing seems to help . I don’t want to try another tablet as Letrozole is apparently the best one for my age and type of cancer to hopefully keep it away……. Only another 8,5 years to take it. 
    my Doctor gives me acupuncture which does help for a few days after treatment. 
    It’s not an easy journey . 
    I wanted to share my experience with you but please talk with the doctor as your situation might be completely different from mine. 
    I wish you luck and hope you get some help.

    kind ragards and hugs

    NannaJ 

  • Hi 

    just started mine eight weeks ago , blurred vision optician seems to think it’s from the tablets but got to go back in six months . Pains in ankles mainly in the night. But getting out of bed in the morning my legs ache. But it does getting better as the day goes on xx

  • Thank you for sharing your experience. It is indeed not an easy journey. Your response has definitely been helpful and I have learned a lot from it.
    Yes I will check with my doctor. 
    kind regards xx

  • Thank you for sharing your experience. It has definitely been helpful. 
    kind regards xx

  • Thanks Lizziebee, it’s really awful to have to deal with but I thank you for sharing. 
    kind regards x