Hello
I’d love to hear your experience of Abraxane aka Nab-Paclitaxel.
Any tips, advice, how it was for you, etc etc
Thanks x
Has nobody been on this?
Im particularly interested in the side effects you experienced
it’s once every 3 weeks so different to Paclitaxel which would have been weekly (I had anaphylaxis).
Thanks
I am replying to bump it up the list. I think its reserved for those who can not tolerate regular paclitaxel. Hopefully someone has had abraxane and can advise
Both the chemo treatments you mentioned can be given on different schedules. I had different types of chemo, the first of which was Abraxane, given mostly together with some immunotherapy. The cycle was 28 days long with Abraxane given on days 1,8 and 15, and the immunotherapy given on days 1 and 15 (so, three treatments per cycle.)
The side effects were not always the same. Nothing happened after the first treatment. After the second I had some diarrhoea. The effect of the drugs on my body was cummulative, so some side effects only started to show up further down the line, such as losing all body hair, fatigue, some skin issues, certain food intolerances, constipation, and 2-3 very short hospitalisations on account of needing a bag of fluids to sort me out. Still, I was more or less functional around the house although in a reduced capacity. Because I was tolerating it relatively well, we kept going and I ended up going into my 10th cycle by the time we stopped (this meant 28 Abraxane and 18 immunotherapy treatments.) I am probably forgetting some of the side effects I experienced on Abraxane because so much has happened since then including another type of chemo, but I hope the above gives you some idea of what someone might experience.
The thing is, response to chemo is very individual. Some side effects are more common than others, but their severity varies. For instance, I did experience nausea, but not as bad as other people on the same treatment.
Hi i had a reaction to pacitaxol so instead was out on Abraxene . I have just finished four rounds of Abraxane which was every 3 weeks .
I have lost all my hair and body hair ,my skin was extremely itchy and I had spots on my face but my oncologist gave me tablets which certainly helped .
Day 2/3 I felt fatigued and low energy which subsided by day 6/7. But the main thing is no sickness which I was dreading would happen . I did have a slight fever on round one and four . But with pain killers felt better .
Everyone reacts different but just speak to your oncologist they will give you meds if you need them for side effects .
Thinkkng of you x
Hi Grey Cats
Thank you for your helpful reply
10 cycles is amazing!!
I will have 3 three-weekly cycles of Abraxane.
I had already done days 1 and 15 of Paclitaxel (low neutrophils day 8 cancelled) then got anaphylaxis on Cycle 2 day 1.
I had Abraxane yesterday and it was ok.
x
Hi Daisy
many thanks for your helpful reply.
We both switched for the same reason.
I will look out for those skin problems. I lost my hair in EC Chemo so that’s already something I’ve got used to.
Hairloss is no biggie. Heart, lung, neuropathy all worry me massively more
Thanks again and I’m thinking of you too xxx
Hi GarageYoga
Glad yesterday went ok and you did not have a reaction .
I had a small amount of neuropathy which was intermittent. but I it has completely gone now . Yes I agree our hair will grow back it is heartbreaking seeing the hair falling out and my head was sore I shaved it all off and then accepted it more I have lots of scarfs and turbans did not get on with a wig .
I’m also hers 2 positive and having this every 3 weeks for a year .
I start my radio therapy next week .
good luck and hope you do not suffer with side effects .
take care .
Thanks x
I agree about not getting on with a wig; I much prefer turbans.
Are you on Abraxane for a year do you mean? I’m only having 4 cycles of Paclitaxel/ Abraxane, but a year of Phesgo injections.
Good luck with your radiotherapy. I hope it goes well and you don’t suffer too much. X
No sorry I had 4 rounds of Abraxene , and Herceptin ( targeted therapy ) is every 3 weeks for a year .
Thankyou I’m sure the radio therapy will be ok . .
Ah ok. Same here then.
I am on Phesgo though rather than just Herceptin. Loads of my lymph nodes are affected so maybe that’s why.
I am dreading neuropathy the most. Encouraging neither of you seem to have had serious issues with that.
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