Predict and decision about taking hormone suppressants. Letrazole and Exemestane

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Hi, I’m new!  I have had bad side effects from Letrozole and Exemestane so my consultant used predict yesterday.   Exemestane was better for me than Letrozole but I am still very tired and have aches and pains etc.      Apparently,  I have an  2% risk, so for quality of life reasons, it has been agreed that I have 3 months break to,see how it goes.   I am lucky as my sentinel node was clear and I only needed radiotherapy. Grade 2.     I just wondered if anyone has had a similar experience and made the decision not to have hormone suppressant meds?  Also how they feel about it and how long it took for the side effects to  go?  

  • Hi Mazz,  Thank you for your reply.   It is difficult to make these decisions isn’t it - but it sounds  like you have made a good plan for your situation which always helps!   I’m sorry you had to go through some chemo. I was lucky - but good to know that the sessions you did have were useful.   I think I blame HRT too as I was on it for a long time after an early hysterectomy and op her to,y because of a prolapse and ah]adhesions.  I was on the pill for quite a while before that.     I’m glad they do so much research now so the next generation can benefit.   Good luck with your recovery and the anastrazole.   I know people who have had no problems too so I hope you are one of them.  With best wishes x

  • Predict doesn't include radiotherapy as it's presumed to be given with lumpectomy.  It would only happen after a mastectomy if the team thought it was higher risk (grade 3, in a few nodes, larger tumour,  small margins etc.  The other thing not included is lymphovascular invasion ( on pathology as LVI present or not present), which can be present with clear nodes and increases recurrence risk slightly. 

    “Remember to look up at the stars and not down at your feet.  Stephen Hawking,