Hi everyone
Just started letrozole 2 months ago and feel my body is ceased up lower back left knee left hand and wrist had 2 lumpectomy s and mastectomy having expander done at present then reconstruction next year maybe August time question is should I be looking to change letrozole for something else or does it settle down after a while
Thanks keep strong everyone
Hi Apple, I felt the same as you when I started, and I had seen a lot of comments on here about the difference in side affects depending on the brand your on. The Accord seems to work The best for most people. Get your doctors to print off your prescription, then call round pharmacist to see who's got the accord in stock before handing your prescription over. Try it, it was life changing for me.
Hi Apple. I've been on Accord brand for 18 months. I'm 66 and still working, albeit now part time. My joints are stiff when I first stand up if ive sat for a while, but no actual pain-and it wears off once I get moving. I wasn't like this before letrazole.
Hair thinning has been a bit harsh, but has settled down. My worst side effect is intimate dryness
Accord brand is definitely worth a try
I too had Accord brand, just asked my GP to request it on the prescription and the chemist got it. I’d done some research and I think that brand was closest to the original, trade name Femara.
I too had aches which tended to ease once I began my day. I had 3 years on that, 2on Tamoxifen and am now 2 years on Exemestane after a recurrence. Yes, the aches aren’t easy to cope with but cope with it I need to as it’s the best way of helping prevent further problems.
hugs xxx
Moomy
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2026 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007