I'm experiencing a lot of joint pain, especially in my knees, since starting letrozole 3.5 years ago. This is getting really painful now and I have been getting sciatica type pain on the rhs of bottom. Sleep is a struggle as everything seems to hurt when i lie down. I'm taking co-codamol at night (2 x 15mg codeine/500mg paracetamol). Really concerned about stopping taking letrozole as terrified of re-occurrence of breast cancer (grade 3 breast cancer oestrogen positive). But I feel my standard of life is restricted as struggling to exercise/walk far/sleep soundly. Has anyone else weighed up pros/cons for stopping letozole before 5 years? Also are the side effects reversable once medication is stopped? Was going to try collagen supplements but these increase oestrogen levels! Has anyone tried these? Thanks x
