I'm on tamoxifen after breast cancer.about 2 years ago. Lump removed, then radiotherapy. Oestrogen positive. First started with letrozole tablets but they caused terrible muscle weakness which affected my mobility. I've been taking tamoxifen for about a year and wondered if it's possible to have a build up which then causes side effects. I get really swollen ankles by the evening. Not too bad in the morning and during the day. The muscle weakness in my leg seems to be returning too. Any ideas?
