Breast Cancer hr. Neg/her2 positive node neg.

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Lumpectomy. Radiation...20 rounds. On letrozole.  Major joint pain and calf pain.  Awful fatigue. Lots of problems sleeping. I've been on Letrozole for 4 months.  Anybody else having trouble with this medicine?

  • Hi  

    I'm sorry that you find yourself here courtesy of BC!  

    I was on Anastrozole, rather than Letrozole, but the coatings of the tablets make a huge difference.  If you are really struggling with this tablet, try asking for a different brand.  When I was on Anastrozole, I had Accord brand and was fine on it, I was then given a different brand - Consilient -  and had exactly the same side effects as you.  I switched back to Accord and was fine.  When I struggled to get Accord, I googled the brands for their coatings' contents and although they are tiny, the difference can be major.

    If you look at this link (above) you can see the brands - clearly you'll NOT offered the ones that cost loads, but if you look at similarly priced ones then you can Google their coatings and see if the different brand makes a difference to your symptoms.  I do hope it does.

    Kindest wishes, Lesley

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  • I’ve been on Letrozole for couple of months mainly feeling tired a lot!! Hot flushes too x