Letrozole and mood

Hi I haven't been on here in a while myself but something prompted me to reach out to this lovely group of ladies this morning.  Firstly, let me say congrats on finding and having your BC discovered and treated early on.  I'm not going into my whole story, but am 3 years out from my surgery and RT.  I was on Letrozole for right at 3 years and did fairly well with it, but as time went on my skeletal issues became pretty awful and I asked my Oncologist about stopping the meds.  Her suggestion was to switch over to Tamoxifen.  I've now been on it for about a month and was horrified to find something akin to menstrual cycles starting again.  Jeepers, I'm 68 and dealt with that mess far too long to go through it again.  And of course I wasn't even remotely prepared for menstruation.  Right now I'm awaiting a consult with my Dr., and hope she's going to switch me back to the Letrozole.  I found that various brands of the letrozole have differing affects on me.  Maybe the brand you're currently taking is the culprit.  Ask your Dr. if they can get your a different brand.  Barring that, perhaps you could research and find some mindful classes that will help with the anxiety.  I never had that issue with Letrozole, but it does so many funky things to your body, that I sure wouldn't rule it out.  Still and all, from this side of the pond, I prefer Letrozole over Tamoxifen.  Just an opinion, but hope it gave you some food for thought.  Mira

Hi Mirabo, thanks for your response.  Having coped with general anxiety for over 30 years, I think I've tried all the relaxation/mindfulness stuff there is!  None of it stops me waking up feeling rubbish... But I will definitely talk to the GP.