Chemo before clear margins??

FormerMember
FormerMember
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Hello everyone!  I was diagnosed with invasive lobular carcinoma. Original imaging predicted it was 8mm so I opted for lumpectomy. When the pathology came back, it was 34mm with all positive margins!  At that point, my surgeon ordered an MRI to access the residual disease. She was sure we must have gotten most of it out  The MRI made another lumpectomy look doable but this time I had 2 positive margins    At this point,  I was finished with surgery and opted for a bilateral mastectomy, however,  my oncologist said I needed to get started on chemo. It had been nearly 3 months getting 2 surgeries, MRI, meeting with plastic surgeons, etc. She said the tumor board all agreed I needed chemo sooner than another surgery. So now I worry about having chemo with positive margins in place.  Will the cancer be more likely to spread now??  Has anyone else ever heard of a situation like mine?  I feel I have been doomed before I've even started.  

  • FormerMember
    FormerMember

    Hi 

    Warm welcome from across the 'Big Pond' you have found yourself in a great place to be at a tough time.

    Quite few have chemotherapy prior or mid way though surgery - It's all about priorities.

    Your original tumour has been removed so it looks like they feel chemo next is the best option as it is a systemic (whole body) treatment. That way if any cells have escaped the chemo will destroy them, it also gets to work on any smaller clusters of cells that 'may' be in the breast(s)  There have been many messages here from those who had chemo prior to surgery that get a full pathological response meaning the tumour can no longer be found on scans. Once the main tumour has been removed any other follow up treatments like chemo, rads, hormone therapy etc is all about reducing the risk of recurrence or secondaries later on.

    So in a word no, the cancer will not be more likely to spread if anything it will be exactly the opposite Slight smile

    Hope this helps reduce your fears and gives you confidence to trust your team, sounds like they have got you covered Thumbsup

    Hugs, G n' J  Musical scoreSaxophoneTrumpet

  • Hi , 

     is right, chemo will indeed help diminish any possible spread and those unclear margins will probably totally disappear!

    i just wanted to pop in to say hi as my sis in law hails from St Louis, and my brother met her there and married! (Yup, read your profile!) 

    Hugs xxx

    Moomy

  • FormerMember
    FormerMember in reply to FormerMember

    Thank you so much!!!  I honestly feel on the verge of tears with relief!  I know there are never any guarantees but I was feeling that circumstances beyond my control had now worsened my prognosis. I just want the same chance as everyone else to beat this!  

    I'm worried about the pathology that will come after my mastectomy. What if the cancer has grown in chemo, what if the response wasn't comp!ete, what if, what if. It can become maddening. 

    You've really explained things so well and I cannot thank you enough.  Thank you also for the warm welcome. I wasn't sure if it was ok for me to be here as I am American.  I personally find American forums to be more difficult as many people are quite competitive with their diagnosis and treatment.  Here everyone seems so entrely supportive which is such a comfort  

    Thank you!

  • FormerMember
    FormerMember in reply to moomy

    Hi Moomy!

    Thank you so much for your reply!  Such a small world, isn't it?  Tell your sister in law hello from me :-).   Do she and your brother visit St Louis very often?

    Hugs xxx

  • Hi again,

    they went back for their Golden Wedding, (I’ve a photo of me posing at the time, under the Arch!) they now live in Texas (slight difference) having lived for some years in SF Bay Area. My brother worked first for Monsanto (hence St Louis) then Bank of America (SF) and then American Airlines, (hence northern Texas, near DFW) 

    he gets around, even in his 80’s, as AA awarded him free air travel for life and they e just got home after a Great Rail journey around Vietnam and Cambodia! Crazy couple! Their sons live all over the world too, LA, Portland and Singapore!

    Hope all goes well for you.....Keep posting 

    hugs xxx

    Moomy

  • Hi

    I had a lumpectomy and no clear margin, I had a two further ops to try and get the clear margins but it unfortunately didn’t happen - so I had chemo from Nov to Jan and then had my mastectomy with implant in early April. I too had moments of mild panic but was reassured that the areas that weren’t got must have been very small. My pathology after my operation showed no way evidence of cancer , was it that there was none left, or the chemo/Herceptin (mine was HER2+) did its job of mopping up ? I will never know. 

    it is a really weird quandary to be in, and hindsight is a wonderful thing , but just try and think it must be very small and the specialists are offering you the best plan for you.

    hope all goes well

    jo x

  • FormerMember
    FormerMember in reply to jowoomot

    Thank you so much, Jo!  I feel so much better!  Everyone on this site has been incredibly kind and supportive. I hope to pay that kindness forward as I progress on my journey. 

    Hugs xxx