Hi everyone,
I was diagnosed with Acute myeloid leukemia in December 2024 and underwent 4 cycles of chemo, including 2 lots of HiDAC chemo. I had the FLT3 gene mutuation and unfortunately there was only a 9/10 donor match and due to having lots of complications during round 1, it was decided too risky for a stem cell transplant. The plan was to stay on a gene inhibitor medication for a few years but unfortunately I relapsed about 6 weeks after finishing my treatment . I'm now back in Hospital having completed FLAG-ida chemo which is much stronger. I'll have another cycle then stem cell at the end of October. Really nervous about the 9/10 match and the implications of this but I have little choice. Has anyone else been in this position please and can share any positive stories?
Thank you in advance 
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Hi again Deb C and sorry to hear about the bumps in the road.
Remember that I don’t have AML but was treated for 2 rare types of T-Cell Non Hodgkin’s Lymphomas.
My brother was my donor for both my Allo SCTs….. (June 2014 then Oct 2015) he was my 10/10 match….. But over the years I have talked with many people who have had a successful Allo SCTs with a 9/10 match….. even a few with a 5/10 match.
The main implications of a mismatch Allo is the donor cells need to work slightly harder, I asked my SCT coordinator about this and she said that it’s not seen as a problem.
