When to get insurance/fit to fly

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Hello, 

I'm currently mid radiotherapy but really want to book a holiday for later in the year to look forward to. 

I'm unsure whether I can book it to secure the holiday and sort my travel insurance after I finish radiotherapy and ask for a fit to fly note etc or if I need to have the insurance in place before I book. 

Has anyone got any experience of this? 

I wouldn't want to book the holiday and then sort insurance after if that will invalidate the insurance..

Also, how soon after radiotherapy will I be able to ask for a fit note and who provides it? 

I will be tamoxifen then at the time of travelling. 

Thank you :-)