Some information re nausea and medication

Hello

My Wife has not been well recently. She has had a few bad ‘ episodes’ recently. Waking up delirious & not her self at all, talking lots of nonsense, After some investigation we have determined it’s the new anti nausea tablets she was prescribed levomepromazine, she takes one every 3 days, the day before her ‘ sick day’ which starts the day after she changes her patches. The ‘episodes’ she has been experiencing occur exactly the day after, so plan to discontinue these and go back to metachlopromide, which are not as effective but without this terrible side effect. Will monitor for the next few weeks and if no more ‘ episodes’ will alert our G.P. to notify the company as a new side effect., although it does have an  interaction, with bisporolol and ramiprill which she also takes, it’s all so complex when on so many meds,  but these ‘ episodes’ have scared the hell out of me. While looking into this I asked the pharmacist about this 3 day cycle of nausea, we can’t see how it’s not linked to her changing her matrifen patches every 3 days. After discussion the pharmacist told me the effacy of the matrifen does decrease just before it’s due to be changed, so putting the new ones on could hit her system amd be the cause of the nausea. I have requested changing her patches from a 100 plus a 25 patch, to two

62.5 patches,  one for the left and for the right arm, but changing them alternate days, with one day with no changes, hoping this will avoid the surge when changing the old 125 to a new 125 in one go.

That may sound complicated, but it was worse than that with many many phone calls to various medical services to try and help her, shouldn’t come down to me working out the reasons behind her problems, with all these health care professionals involved, but so,long as it works, that’s great. Maybe with the new patch regime, maybe she won’t get the nausea so much or maybe not at all and won’t need anti nausea meds 

it’s been a very scary few weeks, thought the cancer had spread to her brain, or has a brain infection, but it looks like it’s just the levomepromazine, so be interesting if anyone else has similar experiences.

thanks

keep safe ano well