This trial is currently underway and will be opening again for more candidates in some locations in due course. I've been provided the info as I tick the boxes. It will open at my unit, Edinburgh Western.
The purpose of the study is to find out if new treatment Modi-1 can be used safely for breast, H&N, ovarian or renal cancer and benefit these types of cancer. Modi-1 is designed to help your immune system attack and destroy cancer cells.
Brief Summary: "The main objectives of this study are to assess the safety, tolerability, immunological activity, and preliminary efficacy of the Modi-1/Modi-1v vaccine, both as monotherapy and in combination with a checkpoint inhibitor (CPI) such as pembrolizumab or nivolumab (where these are standard of care in a non-neoadjuvant setting), in patients with advanced triple negative breast cancer (TNBC), advanced/unresectable human papillomavirus-negative squamous cell carcinoma of the head and neck (SCCHN), high grade serous ovarian carcinoma (HGSOC), or renal cell carcinoma (RCC)."
I'm just sharing as a heads-up, to meet others considering it, or on it. I did a search of the forum and surprisingly didn't find anything.
I have just read the Scancell info on this and it does look interesting. Cancer Research is showing a trial of it for small cell lung cancer, but not yet for other cancers. With PD-1 positive TNBC, my next standard of care would include Pembrolizumab so this is definitely something I will follow with interest.
This is interesting. I don't know if I would be suitable as it has not been mentioned at any of my hospital visits. I am having palliative radiotherapy only for a squamous cell cancer which has spread from my face to my ear. I'll try and find out more about it.
Good luck with your treatment.
I've just started on the trial this week (june 2023). ModiFY Trial Day 1 The update since the injection is that my arm is a right mess!
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2024 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007