Knowing what to say and what not to say

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Hi everyone, I have been supporting a very close friend (more like a 2nd mum) through her cancer journey & she has been so positive throughout the whole process , of late she has been experiencing what can only be described as severe anxiety, she does take medication but it seems to now be having little effect to manage symptoms, recently dose increased by Dr but has left me pondering how I adjust myself to offer support for how shes feeling currently? Has anyone else experienced this with a loved one? Conversations are harder because I can see the effect it is having so making small talk feels the wrong thing? Just wish I could say or do something to help re connect with present moment... welcome any advice