Paclitaxel /Carboplatin

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Hi Everyone 

I'm new to this forum and this is my 1st post . 

I just had my 3rd cycle of paclitaxel and carboplatin yesterday and everything is going OK with side effects not too aggressive thank goodness. However , yesterday I was given the carboplatin before the paclitaxel instead of the other way round . I read that paclitaxel should always be given first to be most effective. Has anyone else experienced this? 

Talking of side effects , my hair is falling out now so I'm off for a head shave today so I won't be able to pretend that I don't really have cancer and that this isn't all a really bad nightmare Upside down 

Wishing you all the best in your battles Kissing heart 

  • Hi  and welcome to the Community.

    This group is a general Chemotherapy discussion group so you ‘may’ connect with others on the same treatment……

    However I do see that you have already joined our dedicated Vaginal cancer support group……  you may want to copy the text from this post and put up a thread in the Virginal group as this will widen your support platform to people with the same cancer - all the best. 

    Mike (Thehighlander)

    It always seems impossible until its done - Nelson Mandela

    Community Champion Badge

  • Virginal Sweat smile sorry , that did make me chuckle!

    Darn predictive text ! 

  • JoyJoyJoy

    Mike (Thehighlander)

    It always seems impossible until its done - Nelson Mandela

    Community Champion Badge

  • Hi it been a while since you posted but just wanted to know how have you been overall with carboplatin and paclitaxel what were your side effects and how often was your treatment was it weekly or every 3 weeks. 


  • Hi , I had 6 weekly cycles . I've now finished treatment and waiting for an MRI to discover if it's been effective 

    Side effects from the paclitaxel/carboplatin included :

    Hair loss from week 2

    Hot itchy skin rashes

    Mouth ulcers 

    Altered sense of taste 

    Nose bleeds

    Low platelets 

    Mild neuropathy in my finger tips

    On the whole these were manageable and my team prescribed stuff to help the rashes and ulcers . The chemoradiotherapy was far worse! 

    Hope that helps. Hope you're OK 

    Best wishes Amanda 

  • Aww bless you. I am happy to hear that it was manageable for you. Do you know what your other 2 drugs will be that you going to have depending on your MRI. 

    Did you end up getting a picc line or port or did you stick with a cannula.

    I'm ok thank you for asking I have my pre assessment tomorrow then treatment starts next week on Wednesday. I pray that my symptoms are also manageable and not to severe.

    Love Txddybear 

  • My treatment was the 6 cycles of paclitaxel/carboplatin. This was then followed by 25 sessions of radiotherapy with weekly cisplatin (another chemo drug) and finally 4 sessions of brachytherapy (internal radiotherapy). I think we have different types of cancer so your treatment will be tailored specifically for you and different to mine 

    During chemo I was also given steroids and antisickness drugs which you might have too

    I wasn't offered a picc line so was cannulated each time . Good luck with your treatment, although I was anxious about starting treatment it was a relief to get started. I hope all goes well for you x

  • Wow, it sounds like you have had a lot. I will be having chemotherapy for 24 weeks, surgery then radiotherapy. That is the plan for me. 

    That's right I will be given steroids and the anti sickness tablets. 

  • Hi

    Just to say that I hope all went well with your 1st chemo and that you're feeling OK 

    Best wishes Amanda 

  • Hi Dorset Girl 

    Hope you are well.

    My appointment didn't go to well I'm afraid. So they put on the premeds did the saline which she put on fast then she put on the antihistamine which was still going in fast as she was near to finishing that I suddenly felt I was going to pass out my body couldn't take it. I told the nurse she alleviated my legs and after abit I was started to feel better. The sister then said to her put the rest in slowly which was fine even when she put on the steroid it was done slowly and I was fine. 

    Then she put saline back on again was put on fast was fine for quite abit but half way through the other nurse came and put it on slowly then after a few minutes I got the same feeling where I was going to pass out so my husband put my feet up again gradually felt better. In-between that time my Temp was going up in one ear it would show something and in the other it would show a other. Long story short they spoke to doctor and he said it was fine for ke to go ahead but I wasn't I said I shouldn't be feeling like this as in Temp up and the rest because I was fine up until I came to the hospital so they have done bloods for any infection and have called me back on Friday to start over again. 

    I will tell them this time to just do it slowly maybe it was too much for my body as my body didn't understand what was happening and it reacted god knows just hope it is all OK on Friday as need to start the chemotherapy as soon as.