Getting up many times in the night to wee.

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My husband has sarcoma. Has been on various treatments. Now on a drug, Selinexor, permanently it appears. He had a pituitary op in 1988 and that affects frequency of weeing. Now he is up as many as 8 or more times in the night. No-one seems to know what to do. Has anyone had experience of this too frequent urination and what they did.