Hi My husband was diagnosed with locally advanced prostate cancer 5 years ago. PSA 9.9 Gleeson 4+5 10 positive cores.Left inguinal node, left obturator node no metastatic disease. Had 6 cycles of Docetaxal chemo followed by external beam radiotherapy and brachytherapy boost. Had 3 years of LHRH injection stopped September 2024.. Since stopping we have 6monthly PSA readings which have increased slightly each time 0.34 latest reading. We have been told nothing to worry about unless it approaches 2ug/L. However with a low PSA at diagnosis should we be worried about the 6 monthly increases although only small.
Hello A65
I agree with your husband's team, nothing to worry about.
He's still got a prostate so there's still going to be some PSA in his bloods and his body will have been removing the dead cancer cells which still contain PSA so yes - it's quite possible for his readings to rise.
It's normal not to take any further action unless he has 3 consecutive PSA rises or a rise above +2.
I hope the above helps.
Best wishes - Brian.
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