49 and just had my template transperineal biopsy this week

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Hello all, recently joined at 3am as going through the process of seeing if I have PC. 

I'm 49 years old and live in West Sussex. My father had Prostate Cancer in late 50's and had a Prostatectomy and my grandfather died with, rather than of Prostate Cancer so its in the family history.

November 2025, whilst visiting Dr for Naproxen for a bout of sciatica, mentioned in passing could I have a PSA test to "stop the other half moaning at me to have it done" - surprised when 2 days after the blood test I got a call from the GP saying levels were raised (4.9 PSA) was in and a finger up the bottom that afternoon and he said he could feel a lump and referred me for a MRI.

MRI completed 2 weeks later and then the letter I didnt want to receive advising they wanted to do a Biopsy. 1st was cancelled in Mid December 2025 due to equipment failure so had to hang about for a replacement date.

My template transperineal biopsy was done on 5th January 2026 and as of the date of joining this Forum (9th January 2026) I'm just waiting on these results and enjoying playing "guess what shade of pink" my wee's going to be!

I'm really.hoping to get alot more answers when I see someone about the Biopsy results as at the moment I feel a bit in the dark. All I know is when they did my MRI I was graded 3 out of 5 so they obviously can see something but dont know what it is yet, hence the biopsy. I note some people seem to have so much information and wonder why the information so far is so scarce though I suppose right.now they may not know much more themselves. 

Anyways, I'm hoping its good news and if is PC has been caught early so have lots of options. Losing the ability for sexual activity following a Prostatectomy is probably the thing playing on my mind most at the moment. 

  • Hello  

    A warm welcome to the club you didn't want to join although I hope you only have a short term membership! Smiley.

    PSA of 2.9 is pretty normal to be honest. A "lump" on the prostate isn't too good and an MRI PI-RADS 3 means they are unable to tell from the MRI if there is anything suspicious there. So it all hangs on the biopsy results. These will give you all the "missing" information.

    I hope for your own sake it's nothing but even if it is, prostate removal isn't always the correct treatment, there's Active Surveillance, Radiotherapy, Hormone Therapy and Brachytherapy to consider.

    Take it easy (easy for me to say!) relax, enjoy life and I am sure you will be fine.

    Do feel free to ask any questions - nothing is too trivial.

    Best wishes - Brian.

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  • Hi BSF  and welcome 

    I didn't know that PSA 2.9 was classed as raised , I thought normal.

    But anyway he felt something so obviously they want to proceed further.

    Just wait for the biopsy results, maybe it isn't cancer,  if it is probably a Gleeson 6 or 7.

    One thing to check if it is positive, what size does tumour show on the MRI.

    Because with that info, PSA, Gleeson, and tumour size and location within gland possibly active surveillance an option.

    Best wishes 

    Steve 

  • Hi BrightonSkyFlyer

    Welcome to the forum and sorry you find yourself coming to the group that no-one wants to join. This is a great place for advice and support.

    It is good news though, that your PSA is very low and if you do have pc have likely caught it very early.

    Even if you do have pc, it's possible that it is so slow growing and not aggressive that no action is needed other than regular tests to keep an eye on it.

    I was in a similar position to you just under 3 years ago. PSA 3.07, family history etc. Had surgery in September 2023. Living a completely full and normal life and have put it all behind me.

    Come back to us when you get the biopsy results with the T NM score.

    Feel free to ask anything.

    Cliff

  • Sorry, the 2.9 was a typo - it's 4.9 (in 40's it should be no more than 2.5) so I know its not as high as others but guessing that's what prompted the investigations.

    AS is my goal but thanks for the information on what I should be asking when I do see my consultant - I shall definitely be taking a pen and pad with me to note everything down as with the biopsy I was just so nervous about the general anaesthetic I just wanted to be in and out as quickly as possible!

  • Hi  PSA of 2.9 wouldn’t normally trigger a DRE (finger up the b..) but well done to your GP.  Maybe you have had a PSA previously at a much lower reading and that raised the alarm.  Anyway PIRAD 3 is very inconclusive so other more accurate tests are required.  Let’s not jump too far ahead until we have the results, but like others on here have said, if PCa is diagnosed it is very likely to be curable.  Please come back with any questions before or with the results.

    Best wishes, David

    Please remember that I am not medically trained and the above are my personal views.

  • Ok, I understand, yes 4.9 a bit above normal, actually mine was similar in 2013 and started me on the inevitable journey.

    All the best 

    Steve 

  • Typo on my original post - PSA is 4.9 here