Lowered PSA score after being diagnosed with prostate cancer

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Hello all. Wishing everyone healthy, happy holidays. 

I had a prostate biopsy on 6/2/22. Prior to that I had a "high" PSA reading of 5.627 on May 18. After the biopsy, two urologists told me that I needed to have a prostatectomy or brachytherapy, no questions about it. Long story short: On 9/6/22 I met with the urologist/surgeon who would have performed the brachytherapy. After he reviewed all my information, it was his suggestion to just observe my situation and not do anything rash. Since he had been referred to me by 3 doctors (including the two who had told me I had to have some procedure done), I decided to trust what he said. Jump ahead to 11/24/22. I had a blood test and it revealed that my PSA was 4.45. This made absolutely no sense to me, but the urologist was quite happy about it and decided for now that we will do AS, with my next blood test schedule on 3/23/23. on 12/7/22 I saw my regular doctor (a cardiologist who is the head of the hospital I go to). He thought this was great news as well. I asked him what would have caused the PSA to go down. I specifically said, "Isn't it the case that if there is cancer present in the body that it naturally grows? And by growing the PSA score would be higher?"

He said that the biopsy is seen as the body as a kind of "injury." (Which, for those of you who have experienced it, I'm sure you would agree.) He said the white blood cells would have rushed in to "heal" the area and that that may have had an impact on the PSA level. He said he thought the AS was a good choice for now, and he said that unless I planned on living till I was 120 (I'm 68), that I needn't worry about it. 

I am a worrier by nature, and it will be on my mind, but this is all quite shocking to me. The 4.45 reading is lower than 3 readings I've had in the past over the last few years. Yes, there will be ebbs and flows in the readings. And I hope to God I do not have to have another biopsy. But for now, I end this year with gratitude, as opposed to how I started it, which was in abject fear. 

I wish you all well. Would love to hear from anyone who's had a similar experience with a lowered PSA score. 


  • Hi Tats

    I know u have posted before although I can't remember all your stats,

    In this particular case I wouldn't worry too much about the PSA which is near normal anyway.

    I assume that the Gleeson is a 6 or 7.

    Probably the most important thing is the Mri, what does that show. I think I remember u saying that the size was about 3mm?

    In which case u  can relax , AS is fine which is also what they are saying,

    best wishes

    Steve

  • Steve, thank you. Wow. You remembered quite a bit. 

    Yes, the size was 3mm and the Gleason was 6 (3 readings) and one was 7. 

    Yes, AS is what I will follow for now. 

    Wishing you good health and happy holidays. 

    -T

  • and to you as well T

    Steve

  • Hi

    I was diagnosed with malignant prostate cancer Gleason score of 4+3 on may 2022 . Before the MRI and biopsy my PSA level was only 3.14 that was tested in April 2022 and referred to uclh. On October 2022, after changing my diet to about 95% plant based. No sugar, no flour and no processed food. Plenty greens and veg. Olive oil and propolis. Anyway I didn't know what I was doing but I panicked and started reading and did what I did. In October 2022 my PSA level was down to 1.86 after insisting to do the test. My GP, a urologist nurse and the surgeon himself were not moved by the news, they were convinced the cancer still there. Anyway the surgeon did the cryotherapy surgery last week, I wore the catheter until yesterday and I feel great so far no side effects yet except from little leaks before passing urine. Too early to shout victory I think. Therefore my case and yours are inconsistent. I don't get it.

    Rez

  • Hi titami53

    Your case and mine are almost the identical but controversial decisions by the experts I believe. I went for cryotherapy surgery last week and  the catheter was removed out yesterday and I feel good already but is too early to shout victory.

    As I mentioned earlier the PSA level went down, in October to 1.86  from 3.14  back in April. but my GP, urologist nurse and the urologist himself were not moved by the results. They were all sure the cancer still there .I discussed it with the urologist on the day of the surgery and he decided to go ahead with it. I couldn't persuade him  to go for AS because it's dangerous to leave it he explained. I have not spoken to him yet after the surgery. The other side of the prostate though is 3+4 therefore it's on AS. What was your Gleason score might I ask?

    Take care

  • There are some more rare prostate cancers that have lower PSA levels so sometimes people can have prostate cancer with a "normal" or low  PSA level.  This is why there needs to be a better, more accurate test than PSA and hopefully with more research there will be but now it is all we have.

  • Hi Rez 

    Hope al goes well, didn't know that u can have cryo on one side and AS on the other unless I have read that wrong 

    Steve 

  • Wait, wait... they were "convinced the cancer was still there" -- but didn't they take an MRI to confirm? I hope the cryotherapy was 100% successful and I'm sorry you had to endure it. 

  • Hi Rez22. The low PSA score is great, and I'm unclear why the surgeon went ahead with the procedure. It is only "dangerous to leave" it if it has shown that it has grown. 

    My Gleason score was something like 3+3 (3x) and one 3+4, if I remember correctly. The cancer (at the time) was contained in one area of the prostate. 

  • But don't we also have MRIs to indicate the size of the cancer? Isn't that also an accurate test?