Can someone explain what MX means under the TNM scheme. My cat scan did not show anything untoward based on a abdomen/chest scan but does not have an M0 grade. Does this mean that because it was not a whole body scan then it would be MX that is it cannot positively say that there is no spread to distant areas.
Mx usually means that they have yet to confirm what the number should be, as you say, because it was not a whole body scan then it cannot positively say that there is no spread to distant areas.
Are they planning to give you a full-body MRI, bone scan and/or PET scan?
In this context, half a scan isn't really better than none, though I suppose a clear chest/abdomen is a start!
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Heinous
If I can't beat this, I'm going for the draw.
Meanwhile, my priority is to live while I have the option.
When I was initially diagnosed I only had a MRI scan covering the pelvic area
That should show any problems within the gland and just outside. Your CT seems clear, what prompted the scan?
U don't say what your PSA is , this can give some clues especially in your case because of the the clear scan
Steve
Steve,
The 'M' is metastases, distant spread, rather than in and around the gland. It can't be confirmed without whole body scans, as PCa is capable of spreading pretty much anywhere.
Mx isn't unusual during the investigations phase, but it will need to be confirmed before treatment decisions can be made.
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Heinous
If I can't beat this, I'm going for the draw.
Meanwhile, my priority is to live while I have the option.
Once you know there's a PCa, usually following a biopsy, treatment options are largely determined by Gleason (how aggressive the cancer is) and TNM.
Tumour is about where in the prostate the cancer is, and whether it has erupted through the capsule, plus what Gleason tells you.
Nodes is about whether the cancer has reached nearby lymph nodes (by direct spread through the lymphatic system). I think a CT can see that, but....
Metastases. are about distant spread (IE via the blood circulation) as we know, bones is very common, but it can be pretty much anywhere.
Only 'whole body' scans can rule out metastases.
My knowledge of scans is not the best, so if others know better, chip in, but I think a combination of MRI and bone scan can usually do the job pretty well, though no scans are perfect, and they can miss microscopic Mets.
When looking at recurrence, PET scans seem to be the best way.
PSA is good for raising alarm bells, leading to a diagnosis. But PSA is notoriously unreliable, and cancer can and does appear without a raised PSA, while a very high PSA usually, but not always, flags a cancer.
Once you have the diagnosis, PSA alone is not useful at all, BUT *rises* in PSA can show there's a new problem, or that (for example) hormones have stopped working. And a *fall* in PSA can often tell you that a treatment is working.
But you can rarely be sure on two PSAs; you really need at least three tests to be sure of a fall or rise (because PSA is so unreliable).
The *RATE* of rise or fall can also be important: a fast rise suggests a serious worry.
I hope all that made sense!
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Heinous
If I can't beat this, I'm going for the draw.
Meanwhile, my priority is to live while I have the option.
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