I am caring for my husband who has had prostate cancer since 2009. His psa on diagnosis was 26 and he had a Gleason score of 9. Was immediately put on Zoladek, and had EBRT as well as HDR Brachytherapy. All went quite and low PSA till 2012 when on rising PSA he had HIFU and within the year also had Nanoknife. In 2017 PSA rising and Cancer spread to spine, and ribs. Spent 18 months on Arbetirone and Prednosilone and Denosumab. PSA never went below 7 and after Bone Scan Cancer in 2018 cancer extensive in bones. In March 2019 started six Radium 223 injections. Bone Scans showed stable and no new spread. In April 2019 had extensive bilateral pulmonary embolism and dvt in left leg. Psa creeping up and now 154. Alkaline phosphate level 306. In October hospitalised with septic arthritis. Next standard treatment chemotherapy but consultant not keen as doesn’t think Hubbie is strong enough. Enzalutimide not possible due to heart complications after pacemaker fitted after Arbiretirone. He is very fatigued, and has dizzy spells. Nausea is an issue, often breathless and only short term mobility. Mostly in wheelchair and sleeps on and off most days. Constipation a huge issue. He is very frustrated as quality of life now diminished. Is this standard and do most patients become bed bound. Other than wrist there is no pain which confuses me, is there always pain?
