Hello,
Please have a read of my profile which details our journey so far.
So as some of you are aware, Paul has recently been for scans due to psa rise, he has no new symptoms.
Good news - bone scan show improvement in 2 mets (L1 spine and pelvis), no progression in other 4 mets
Not so good news - CT scan has shown new lesion on L2 spine (strangely not shown up on bone scan
) and psa has now risen to 4.....increase of 1.5.
No organ or lymph nodes involvement.
Next steps - appointment with Oncologist next week, there is a question of whether Paul has already moved from castrate sensitive to castrate resistant disease which obviously reduces treatment choices and likely have poorer prognosis although I am not sure why the are talking about him becoming resistant already when he has only just taken the Abireratone, he hasnt tried anything else? Usually resistance happens 2-3 years at least into treatment so this is a massive blow.
Paul has to have biposies taken too, these weren't done on initial diagnosis due to high volume disease and because he started Degarelix straight away but now they must be done to decide on treatments moving forward.
PSA bloods remain monthly, scans to be repeated in 3 months.
Any words of advice greatly appreciated. I will update my profile too
Hello Polly1912
Well the good news is Paul's team look to be on the ball with trying to find out the reason for the increasing PSA and they are looking at all options.
* You have already mentioned targeted radiotherapy - perhaps now is the time for this.
* I can't see the point in a biopsy as the result will be affected by Paul already being on Hormone Therapy.
* I just wonder if a change in his HT treatment might make a difference - I have heard of people being resistant to one drug but not another - food for thought?
I wish you both well with your oncology meeting later in the month - do let us know how you get on.
Best wishes - brian.
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