Prostate cancer

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Hi i am new to this site .In may of last year 2025 i was diagnosed with prostate cancer my local hospital pulled out all the stops and i was given a MRI and CT scan very quickly and it was found that it had gone to my bones . my first blood test showed that my PSA level was 164.5  .and a appointment was made for me to see a oncology doctor who recommended that i have hormone treatment and chemotherapy this i agreed to . the day after my first chemo i felt like superman on steroids this lasted for 5 days on the 6th day i crashed and was rushed in to hospital with sepsis and organ failure. I spent 5 days in a isolation  room in aaeu having 24 hr care every day thanks to the wonderful doctors and nurses .After a week at home recovering i received a phone call from oncology telling me that my next chemo   treatment was in 7 days time which i declined as i did not fell well enough to have chemo  and that i was very worried  about getting sepsis again . The oncologist was  not very happy with my decision but accepted this . I have now been on Darolutamide and hormone treatment for the last 6 months . Now my PSA levels have gone from 5 to 24 and  i have had a MRI and CT scan   again and have been told that i now have 2 small lesions on my spine and that i will need some form of chemo again  i am very worried about this in case i get sepsis again. Has any body experienced  this      

  • Hello  

    A warm welcome to the group although I am so sorry to find you joining us.

    Worry about things like sepsis is always there with a cancer diagnosis or not as it's something you don't "catch", it rears it's head when your immune system over-reacts to something else in your body it's unable to cope with.

    If your medical team are aware of your previous reaction to chemotherapy I would think that during these new sessions your team will be watching you like a hawk monitoring your temperature and bloods on a regular basis. You need to talk to your team about your worries and ask what  precautions they will be taking for you.

    Have you asked your team if the "2 small lesions" can be treated with "targeted radiotherapy" as this treatment has come on in leaps and bounds in recent years.

    Best wishes - Brian.

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  • Hi Brian thank you for your reply to my post . At my next appointment which is at the end off march i will keep your comments in mind . I have a lot of respect for my local hospital here on the isle of wight but my oncology department is on the main land and i have found  that there is a difference in care shall we say most of my information comes from Jo my Macmillan nurse who is very good .They have told me that there are 3 types of treatment but so far i do not know what they are thank again Fred

  • Hello  I wondered if this link might help you to help yourself if you do accept starting chemotherapy again.

     Hubby about to start chemo 

    I can concur with Brian that I would also ask whether you might be a suitable candidate for targeted radiotherapy on the spinal lesions. One other thing I can add is that my husband was given Filgrastim after each chemotherapy session to boost his immune system. How your body reacts to the chemotherapy is a lottery and no one can predict whether you will have a bad experience again. Speak to your medical team and let them know of your fears, asking them what they intend to do in order to reduce the likelihood of having to deal with sepsis again.