Enzalutamide and Prostap stopped

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My husband, 77 has had an excellent response to enzalutamide and prostap for almost four years. He had a cardiac event (the enzalutamide was stopped then) last month and is now four weeks post quadruple bypass. He's making a remarkable recovery but when we met with the oncologist yesterday we were told that both the enzalutamide and prostap would not be resumed because of cardiac concerns (they were not specific about this, and his psa is undetectable) and that he would go on relugolix only now. This is despite his discharge letter from the bypass surgery saying that from a cardiac perspective they were happy for him to restart the enza. We are feeling distressed about this, has anyone here had a similar experience?

  • Probably something to take up with the hospital again if it’s causing distress. In multi risk scenarios like this which is more concerning. Maybe try to get a clearer answer to this. Does the prostate cancer benefit outweighs risks of cardiac event or not? 

  • Hello  

    Thank you for the update. It's medical advice from a professional oncologist so I can't disagree with it. Your husband as you say 

    He's making a remarkable recovery

    and his PSA is undetectable. It's possibly a medication clash - however as long as he's having regular PSA tests his oncology team will be keeping an eye on him.

    All I can suggest is you contact the oncologist and ask for an explanation as to why he's had his cancer medication changed.

    Best wishes - Brian

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