Good Morning all. Just out from seeing my Consultant after my 1st Biopsy didn’t match my MRI so we went for a 2nd biopsy to get the “full picture”. So they took 11 samples from the tumour this time (targeted biopsy) and 10 have come back as cancerous but all 10 are Gleason 6 which is what I got the 1st time (took 4 samples from tumour initially and only one came back as cancerous)
Now the Tumour is 2.6cm and he still believes there is more cancer in there but I’m happy to go on Active Surveillance for next 6 months. So PSA blood check in 3 months (at start of month PSA was 3.2, 50 years of age) and an MRI in 6 months so see if tumour is growing etc. Not broken through the capsule consultant said. He said it’s a 50/50 call. The normal process with a Gleason. 6 is to go on AS but he’s just worried with the amount of cancer that I have that there is always a risk in waiting. He stated that he could do an aggressive operation and save a good bit of the nerve endings. So I think the sensible thing is to wait and see how the next 6 months pan out and just take it easy and avoid as much stress as possible. Thanks for all the wise words of wisdom from the community over the last 7 months too
Hello Dave (Dave HS)
Thank you for taking the time to update everything. Everyone has their own personal journey and we are all different - yours is yet another "interesting" one.
I agree 3 monthly PSA checks are a good idea and yes another MRI in 6 months is a good idea too. Sit back enjoy life and let's hope for no change.
he could do an aggressive operation and save a good bit of the nerve endings
Just a word on the above - he's a surgeon so that's his bread and butter, there are other options down the line once you see an oncologist.
Best wishes - Brian.

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Definitely worth taking some time to consider.
Normally I would think the key factors to watch are PSA velocity and PSA doubling time. Both need a few readings to give useful accuracy and are the primary outputs of AS. Approximately a years worth (4-5 results) of data.
With a large tumour like 2.6cm the MRI could well be the determining factor for predicting a staging upgrade to T3. So that would be my priority.
My first PSA monitoring test is 24 Feb and I will be posting the analysis as I progress. Using the same mathematical methods as used in the big trials. Unfortunately with only my data, so no Cox proportional hazards model or the deep learning Cox-Sage method which would really interest me with implementation of AI in prognostic prediction. Hopefully be of interest to others on AS.
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