I have posted a few times over the last few days and thank you to those who have already given some really valuable advice about treatment options......but we need more!!!.....so our options are -
1. Stay on Degarelix only (he will be on this for life)
2. Take Degarelix and add either abireratone, Enzalutamide or Apalutamide
3. Triplet therapy - Degarelix, darolutamide and docetaxel.....
My bio has all relevant details.
We feel really torn, triplet therapy seems sensible.....seems like many men tolerate it well, can you go on holiday during chemo breaks? Thinking about immune system etc.
Paul is really well on the degarelix, maybe adding in an oral HT would be best.....Oncologist definitely leaned towards this option but triplet therapy appears to be recommended for widespread bone mets.
Only one we think we have ruled out is option 1, not sure why..
We understand everyone responds differently, even with same diagnosis but we are really keen to hear from you....this is such a tough decision, we want to squeeze as many years as we can in
Hi, I've read on here and various other places that triplet therapy is a reasonably new, and successful first line approach for someone with Pauls diagnosis, but for maximum efficacy the docetaxel has to commence within 12 weeks of starting HT (a time frame you are well within atm). I'm fairly new here and am very appreciative of the help on offer here also. No doubt someone with bags more knowledge about this will be along soon.
Hope you get a plan sorted asap, and all the best moving forward
Thank you! Yeah the oncologist mentioned the time frame, she has given us until end of September which will be 13 weeks and she says this would be ok to start triplet therapy. Paul really doesnt seem keen to go down this route, even with the evidence, he feels so well and doesnt want chemo to mess that up!
Am sure we will make the right decision.
Hope you are doing ok️
Ah,ok, I get that. If it helps I had my 3rd cycle of Docetaxel (148mg) today for locally advanced, I've had limited mild side effects, and no impact on my quality of life or day to day goings on whatsoever, but I understand we are all different. I'm 54 btw, and pretty fit.
You will make the best decision for You.
I'm all good and feeling great, thank You
Hello! I hope you're both doing well, and it's great to hear positive feedback so quickly from the Degarelix.
I opted for triplet therapy and it seemed to work well for me with minimal side effects (I also wore a cold cap so kept onto my hair). I understand your husband's concerns about the chemo, and I guess it's hard to predict anyone's side effects in advance. Perhaps I was lucky! But if you are intending on going for it, the impact on his immune system does mean being immuno-compromised so more susceptible to infection and illness. Travel insurance could also be problematic until the cycles are finished.
However, with good health and relative youth on my side, we felt that the triplet therapy offered the best chance of a strong response.
Good luck with making the right decision and feel free to ask me any questions
Hello , we are both doing well, adjusting to the new normal
......thank you for the advice, I had read your profile awhile back when we were keen to be offered the triplet therapy. I think reading all the consent forms etc given my oncology has freaked us both out a bit, understandably
.
Paul is definitely edging towards option 2 and leaving chemo for later but we agreed to get some info from here first, we still got time to make the decision.
Great to hear your experience ️
Afternoon Polly I might have it wrong but I'm sure I have heard you can have another 6 rounds of docetaxel as long as it's after a certain length of time and the patient responded well the first time.
Hi Polly, this is my first post so not added the bio yet. My partner has been on triplets therapy since May (last chemo on 2nd September) and has coped well with it except the first cycle was hard, mainly due to not knowing what to expect. He has been very active and some days been doing stuff up to 12 hours a day despite me saying to him to pace himself. He wore cold cup because it was his daughter's wedding in August and managed to keep his hair. We found keeping a diary is really helpful as each cycle follows similar pattern.
Hi Polly it's me again, I have watched a Dr Mark Schotz on utube he is an American oncologists of 40yrs who specialises in prostate cancer he does explain an awful lot.
Hello , thank you for replying, and welcome to this forum although sad under the circumstances. It's a great place for support and advice.
Great to hear that your partner has responded well to the triplet therapy I sometimes wish the oncologist had made this decision for us
All the very best to you and your partner️
Hello, yeah I think you are right there, am sure I read that myself️
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