My last post here was a bit negative as my PSA test and histology report were a bit worrying. I have had time to process and a being as positive as I can but still have a nagging feeling in the back of my head. The consultant letter stated:
Final histology: grade group 5 (4+5=9), pT3b N0 M0, margins negative
PSA 14/04/2025 = 0.04.
Seeing pT3b is concerning. And then in his notes:
We discussed that you had high volume high grade disease and at this stage thankfully with negative margins and nodes we will pursue PSA monitoring however, if your PSA were to rise in the future then we would need to consider salvage therapy.
The “however” also feels concerning. I know there is nothing I can do and just need to wait for the PSA monitoring, but seeing other T3a and T3b stories here makes me worry as I went into surgery classed as T2a from the MRI scan. Has anyone else experienced a move in classification after surgery and histology?
However… On the big plus side, 9 weeks after catheter removal and I am on day 5 of being completely pad free. No leaks! Feeling very liberated and happy about that!!
Hello Fzh2p0
I was a Gleason 7 - I had a TURP operation and the "chips" from my Prostate went off for examination.
I was then "upgraded" to a Gleason 9 - Thank you very much!! !!
You are doing well - dry and as my friend Alpine Wanderer always says "histology is king" and your surgeon said
margins negative
Those two words are magic - he's got everything!!
Carry on - you are doing so well - you may well have been upgraded BUT the basta*d is sat on the surgery side in a silver dish - not going "walkabout" - happy days.
You should be fine.
Best wishes - Brian.
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Hello Fzh2p0 . You seem to be doing well at the moment but I can understand your concern.
I looked for the figures of upgrade and downgrade in the UK but the latest figures I can find relate to surgery done up to 2016 and the initial biopsy was by the TRUS method. Since then biopsies have improved along with the use of MRI and bone scans at the initial diagnosis stage so I would expect the incidence of change to reduce.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6798468/
Hopefully all your cancer ended up being removed but nowadays there are well practiced protocols in place to deal with a recurrence if it does occur with the aim of keeping you on the curative pathway. Just keep an eye on your PSA and if it does start to rise make sure that it stays below 0.2 but act if it goes above.
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