I've been given a low grade prostate cancer diagnosis: localised prostate carcinoma Gleason 3+3=6. I'm 56, healthy, very few symptoms (slight change in pee flow, but this is stable)
I had a biopsy in July and Oct 2022 (the first one did not tally with the MRI, so I had the second one, which did). I had another MRI in Sept 23, which showed a slight improvement in prostate abnormality. My consultant wants me to have another biopsy, as part of an 12month check.
I'm not keen, as I found the biopsy quite traumatic - mostly the after affects, of having blood/discoloured semen for several months. I knew this was a possible side effect, but it was very alarming, and impacted on sex, my sense of my sexuality, attractiveness, vitality and potency.
I feel I'm on a medical conveyor belt, and under pressure to have the biopsy or be taken off the active surveillance programme.
I find it hard to know where I put my trust.
I know I’m healthy, low risk, and yet I am frightened and anxious. I think I’m still processing the diagnosis, but feel the pressure from the medical interventionist model.
My preference was to wait another year, keeping an eye on 3 monthly PSAs (they are mostly stable, at 8.9), and then have another MRI, and if there were negative changes, to have another biopsy then.
Do I follow my instinct, to wait, or follow the pressure from the consultant? If I wait, how do I manage anxiety, fear, uncertainty?
I was wondering how others have navigated this?
Hi Paul
Your experience is very similar to mine.
I had a 38 core biopsy in 2017. I was out of hospital the same day but the problems started afterwards. I had bleeding for several weeks and nothing worked as well as it did before. I get flare-ups of prostatitis ever since the biopsy.
The biopsy found one spec of Gleason 6, but not in the PIRAD4 zone identified by the MRI.
Now I'm seven years into active surveillance. I have been offered more biopsies and various treatments (private sector) but I have refrained from them all. I have had annual MRIs and only once did they say PIRAD4, so I had a re-review and the second opnion was PIRAD3.
Try not to get stressed. Gleason 6 is just something you need to keep an eye on. I found an NHS paper which says one in 3 men over 50 have some cancer cells in their prostate.
You can read a bit more in my profile if you want.
Best wishes
David
Be positive ! Your disease has been detected at an early stage so your prognosis should be very favourable. I think an annual MRI would be sensible only followed by a biopsy if there is a change in the imaging or every 2 years for routine monitoring.
Biopsies do cause trauma to the prostate and given your experience you are right to try and avoid unnecessary procedures.
I had a 24 core biopsy trans perineum and did get some immediate bleeding but this mostly cleared in a matter of days.
Gleason 3+3 is low risk disease and may never develop into something that needs treatment. So count your blessings !
Hi Steve
Thanks for taking the time to reply.
It would be 3 biopsies. The 1st one was nul and void, as it was done by an NHS outsourced company, and came back with no cancer, which did not tally with the MRI, so was done again, inhouse to the NHS.
The most recent MRI says: "there is an improvement in the abnormality of the prostate. The previously demonstrated right peripheral zone is Likert 4 with small right mid gland Likert 3 lesion."
and the one in July said: "for localised prostate carcinoma Gleason 3+3=6 since May 2022 with a PSA of 11.2ng/mL. MRI scan at that time confirmed Likert 4 lesion with focal atrophy in the right lobe of the prostate.
I think the consultant wants to do another biopsy to compare with the last one.
So to date, I have just the one biopsy gleeson of 3 + 3 = 6.
all the best,
Paul
Ok Paul, a bit clearer.
So it is a low grade cancer, that's obviously good.
Suppose one way to avoid another biopsy is to start treatment as u will probably have to go down that route at some stage
Difficult one but I do remember I declined a second biopsy , just didn't want to go thru it again.
Best wishes
Steve
Hi Paul
As I said in my original post : Gleason 6 - PSA.8.9. Listen to your medical team. I am aware all is well at present but the PSA is up. At some point medical intervention will required - my view and Grundo above is start to get it treated before it gets too bad.
Honest opinion - not a medical one!! Best wishes - Brian.
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