Prostap vs Zoladex

I’ve been on Zoledex for a good while and a couple of injections ago someone at the GP surgery decided to order a Prostrap instead

the nurse spotted it and wouldn’t use it until my consultant had said ok

the consultant said it should be Zoledex and I got the impression it was a cheaper alternative but I don’t know if it performs as good as Zoledex?

goog luck with it all SteveB

Thanks for your reply.  Looking on NICE website there is not a large difference in cost, for those interested the links are below:

bnf.nice.org.uk/.../leuprorelin-acetate.html
and

https://bnf.nice.org.uk/medicinal-forms/leuprorelin-acetate.html

I think if Prostap injections are less painful there might be something said for it.

Good luck on your journey Steve

Hi  SteveB following my first Zoladex LA injection at the hospital, I was offered Prostap by my GP on the basis that a) the hospital had supported it and b) the injection would be less painful than the Zoladex injection.

I suspected a cost benefit but could not find anything that suggested Prostap is an inferior product.

I have obstructive sleep apnoea and I wear a CPAP mask.  In the three weeks since my Prostap jab, my AHI figures have become (much) worse.  It could be a coincidence, but I will do more research on this.

Kind regards
Chris M

Nottingham UHT Oncology seems to favour decapeptyl over the 2 mentioned alternatives. I guess mainly on grounds of significant cost savings with no obvious differences in efficacy.

Thus:

"Prostate Cancer
NICE clinical guidance on Prostate cancer does not recommend which GnRH analogue should be prescribed. The selection of GnRH analogue should be driven by the licensed indications and evidence for use, the side-effect profile, the type of administration schedule desired and cost considerations.

There is no conclusive
evidence to suggest that one GnRH analogue is more effective or has fewer side effects than other analogues for the treatment of prostate cancer. Triptorelin (Decapeptyl SR®) is significantly less expensive to the NHS than other gonadorelin
analogues and its preferential use could achieve significant cost savings across the
health community. Triptorelin is administered via a smaller needle (20 gauge) compared
with goserelin LA 10.8mg (14 gauge), minimising patient discomfort.
The use of triptorelin 6-monthly (Decapeptyl SR® 22.5mg) reduces the number of
appointments needed for administration. Patients with a stable PSA currently
prescribed a 3-monthly dosing schedule can be switched to a 6-monthly schedule ......" (Trust guidelines.)

The default seems to be same as back in 2021.

Good luck, Dave.

They put a cream on target area with my zoladex injection ,very little pain 

All of my HT injections were Prostap and all were painless if that report is of any reassurance.

Likewise - alternate arms.

It's an ongoing debate, arms or stomach. Mine were in the stomach but as yours, alternate sides.

My personal thought would be that, if it is working for you, then stick with a winning formula.

Don't fix what isn't broken.