Hi Group, I am supporting my Dad who today has been told his prostate cancer has metastasized to his bones. He has been given a choice of Chemo (Docetaxel with GCSF) or Enzalutamide. We have a few days to decide. Can I ask around the severe risk of infection with the chemo, does this mean shielding whilst the 3 weekly sessions of 6 are complete - or to shield only whilst the week of treatment every three weeks is required? Dad is a Full time carer for my mum with Alzheimer's and I am trying to give him facts to make a decision. Also if anyone is on these treatments can you offer any advice. Thank you in advance
Hello HLR1, has your Dad started PROSTAP or Zoladex hormone therapy already? When was your Dad diagnosed? What treatment has he had so far?
The early addition of chemo or second line hormone therapy drugs like Enzalutamide or Abiraterone have been shown to improve outcomes.
I think there are a number of men who have gone down the Enzalutamide route rather than Chemo during the COVID-19 pandemic.
Both treatments will have side effects however so it would be worth checking them out before deciding.
Best wishes,
Ido4
HiHLR1
There is a difference between chemo and Enzalutamide both have side effects doxcetaxel possible the worst of the two, with me it was hair loss mega hot flushes, full body sweats, fatigue and tiredness plus some muscle pain and brown nails. I might be one the ones it affected badly with Enzalutamide I got lethargic tired out of sorts hot sweats and muscle pain again this could just be me.
hope that helps
keep safe
Joe
Hi Ido4. Yes Dad restarted the prostap on the 27th January. Back in 2015 he was diagnosed , had radiotherapy then entered the stampede trial. Three years of treatment and then just monitoring. His PSA jumped in 6 months from 2.2 to 18.7 in January . Now the bone scan/mri/ct lead us to this decision. Its a hobsons choice. Dad is 77 years old
Hi HLR1, I am so sorry his PSA has jumped. It is a very difficult choice to make as you have said. Here’s hoping the PROSTAP plus Enzalutamide or docetaxel will bring his PSA back down and keep things under control.
Ido4
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